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    Taf15 TATA-box binding protein associated factor 15 [ Mus musculus (house mouse) ]

    Gene ID: 70439, updated on 23-Jun-2021

    Summary

    Official Symbol
    Taf15provided by MGI
    Official Full Name
    TATA-box binding protein associated factor 15provided by MGI
    Primary source
    MGI:MGI:1917689
    See related
    Ensembl:ENSMUSG00000020680
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Taf; 68kD; TAFI; 68kDa; Taf2n; TAFII68; 2610111C21Rik
    Expression
    Biased expression in CNS E11.5 (RPKM 81.2), CNS E14 (RPKM 33.7) and 12 other tissues See more
    Orthologs
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    Genomic context

    See Taf15 in Genome Data Viewer
    Location:
    11; 11 C
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (83363897..83397569)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (83473073..83506743)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (83286610..83320242)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene growth arrest-specific 2 like 2 Neighboring gene RIKEN cDNA 1700020L24 gene Neighboring gene matrix metallopeptidase 28 (epilysin) Neighboring gene predicted gene, 32650 Neighboring gene HEAT repeat containing 9 Neighboring gene predicted gene, 23247 Neighboring gene chemokine (C-C motif) ligand 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables RNA binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables mRNA 3'-UTR binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within gene expression IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within mRNA stabilization ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    TATA-binding protein-associated factor 2N
    Names
    TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68 kDa
    TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA binding protein 56)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027427.3NP_081703.1  TATA-binding protein-associated factor 2N

      See identical proteins and their annotated locations for NP_081703.1

      Status: VALIDATED

      Source sequence(s)
      AK051568, AL596122
      Consensus CDS
      CCDS25168.1
      UniProtKB/TrEMBL
      Q8BQ46
      Related
      ENSMUSP00000021018.5, ENSMUST00000021018.11
      Conserved Domains (4) summary
      COG0724
      Location:221317
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12535
      Location:230315
      RRM_FUS_TAF15; RNA recognition motif in vertebrate fused in Ewing's sarcoma protein (FUS), TATA-binding protein-associated factor 15 (TAF15) and similar proteins
      sd00029
      Location:356377
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      pfam00641
      Location:352382
      zf-RanBP; Zn-finger in Ran binding protein and others

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      83363897..83397569
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030246301.2XP_030102161.1  TATA-binding protein-associated factor 2N isoform X1

      Conserved Domains (5) summary
      PTZ00110
      Location:469
      PTZ00110; helicase; Provisional
      cd12535
      Location:197282
      RRM_FUS_TAF15; RNA recognition motif in vertebrate fused in Ewing's sarcoma protein (FUS), TATA-binding protein-associated factor 15 (TAF15) and similar proteins
      TIGR01622
      Location:106280
      SF-CC1; splicing factor, CC1-like family
      sd00029
      Location:323344
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      pfam00641
      Location:320349
      zf-RanBP; Zn-finger in Ran binding protein and others
    2. XM_030246302.2XP_030102162.1  TATA-binding protein-associated factor 2N isoform X2

      Conserved Domains (5) summary
      PTZ00110
      Location:469
      PTZ00110; helicase; Provisional
      cd12535
      Location:178263
      RRM_FUS_TAF15; RNA recognition motif in vertebrate fused in Ewing's sarcoma protein (FUS), TATA-binding protein-associated factor 15 (TAF15) and similar proteins
      sd00029
      Location:304325
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      pfam00641
      Location:301330
      zf-RanBP; Zn-finger in Ran binding protein and others
      pfam12273
      Location:102153
      RCR; Chitin synthesis regulation, resistance to Congo red
    3. XM_030246304.1XP_030102164.1  TATA-binding protein-associated factor 2N isoform X3

      Related
      ENSMUSP00000119836.2, ENSMUST00000133170.2
      Conserved Domains (3) summary
      cd12535
      Location:35120
      RRM_FUS_TAF15; RNA recognition motif in vertebrate fused in Ewing's sarcoma protein (FUS), TATA-binding protein-associated factor 15 (TAF15) and similar proteins
      sd00029
      Location:161182
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      pfam00641
      Location:158187
      zf-RanBP; Zn-finger in Ran binding protein and others
    4. XM_030246305.2XP_030102165.1  TATA-binding protein-associated factor 2N isoform X4

      Conserved Domains (3) summary
      sd00025
      Location:89110
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      pfam00641
      Location:85115
      zf-RanBP; Zn-finger in Ran binding protein and others
      cl17169
      Location:148
      RRM_SF; RNA recognition motif (RRM) superfamily
    5. XM_036156982.1XP_036012875.1  TATA-binding protein-associated factor 2N isoform X4

      Conserved Domains (3) summary
      sd00025
      Location:89110
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      pfam00641
      Location:85115
      zf-RanBP; Zn-finger in Ran binding protein and others
      cl17169
      Location:148
      RRM_SF; RNA recognition motif (RRM) superfamily
    6. XM_036156984.1XP_036012877.1  TATA-binding protein-associated factor 2N isoform X4

      Conserved Domains (3) summary
      sd00025
      Location:89110
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      pfam00641
      Location:85115
      zf-RanBP; Zn-finger in Ran binding protein and others
      cl17169
      Location:148
      RRM_SF; RNA recognition motif (RRM) superfamily
    7. XM_036156983.1XP_036012876.1  TATA-binding protein-associated factor 2N isoform X4

      Conserved Domains (3) summary
      sd00025
      Location:89110
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      pfam00641
      Location:85115
      zf-RanBP; Zn-finger in Ran binding protein and others
      cl17169
      Location:148
      RRM_SF; RNA recognition motif (RRM) superfamily
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