U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Slc36a3 solute carrier family 36 (proton/amino acid symporter), member 3 [ Mus musculus (house mouse) ]

    Gene ID: 215332, updated on 21-Apr-2024

    Summary

    Official Symbol
    Slc36a3provided by MGI
    Official Full Name
    solute carrier family 36 (proton/amino acid symporter), member 3provided by MGI
    Primary source
    MGI:MGI:2665001
    See related
    Ensembl:ENSMUSG00000049491 AllianceGenome:MGI:2665001
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PAT3; TRAMD2; tramdorin2
    Summary
    Predicted to enable amino acid transmembrane transporter activity. Predicted to be involved in amino acid transport and proton transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human SLC36A3 (solute carrier family 36 member 3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 33.3) See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Location:
    11 B1.3; 11 32.13 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (55015641..55042548, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (55124815..55151722, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene ATP synthase peripheral stalk-membrane subunit b, pseudogene Neighboring gene major urinary protein, pseudogene 22 Neighboring gene STARR-positive B cell enhancer ABC_E6986 Neighboring gene STARR-positive B cell enhancer ABC_E6987 Neighboring gene solute carrier family 36 (proton/amino acid symporter), member 3, opposite strand Neighboring gene predicted gene, 31688 Neighboring gene STARR-positive B cell enhancer ABC_E3952 Neighboring gene solute carrier family 36 (proton/amino acid symporter), member 2 Neighboring gene solute carrier family 36 (proton/amino acid symporter), member 1, opposite strand

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (1) 
    • Endonuclease-mediated (2)  1 citation

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables L-alanine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables L-proline transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables amino acid:proton symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables glycine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in L-alanine transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in glycine transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in proline transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in proton transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in vacuolar membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    proton-coupled amino acid transporter 3
    Names
    proton/amino acid transporter 3
    solute carrier family 36 member 3
    tramdorin 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001363468.1NP_001350397.1  proton-coupled amino acid transporter 3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK132910, AL713870, AL772357
      Conserved Domains (1) summary
      cl00456
      Location:39361
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    2. NM_172258.4NP_758462.2  proton-coupled amino acid transporter 3 isoform 1

      See identical proteins and their annotated locations for NP_758462.2

      Status: VALIDATED

      Source sequence(s)
      AF453745, AL713870, AL772357
      Consensus CDS
      CCDS24708.1
      UniProtKB/Swiss-Prot
      Q811P0, Q8CH37
      Related
      ENSMUSP00000020502.3, ENSMUST00000020502.9
      Conserved Domains (1) summary
      cl00456
      Location:52458
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      55015641..55042548 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011248898.3XP_011247200.1  proton-coupled amino acid transporter 3 isoform X2

      Conserved Domains (1) summary
      cl00456
      Location:52426
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    2. XM_006532829.4XP_006532892.1  proton-coupled amino acid transporter 3 isoform X1

      See identical proteins and their annotated locations for XP_006532892.1

      UniProtKB/Swiss-Prot
      Q811P0, Q8CH37
      Conserved Domains (1) summary
      cl00456
      Location:52458
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    3. XM_011248899.1XP_011247201.1  proton-coupled amino acid transporter 3 isoform X3

      See identical proteins and their annotated locations for XP_011247201.1

      Conserved Domains (1) summary
      cl00456
      Location:39361
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    4. XM_011248900.1XP_011247202.1  proton-coupled amino acid transporter 3 isoform X4

      Conserved Domains (1) summary
      cl00456
      Location:15329
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain