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    Klhl33 kelch-like 33 [ Mus musculus (house mouse) ]

    Gene ID: 546611, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Klhl33provided by MGI
    Official Full Name
    kelch-like 33provided by MGI
    Primary source
    MGI:MGI:3644593
    See related
    Ensembl:ENSMUSG00000090799 AllianceGenome:MGI:3644593
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EG546611
    Summary
    Orthologous to human KLHL33 (kelch like family member 33). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in cerebellum adult (RPKM 5.2), heart adult (RPKM 2.7) and 8 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Klhl33 in Genome Data Viewer
    Location:
    14 C1; 14 26.29 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (51126038..51134940, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (50888581..50897483, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene telomerase associated protein 1 Neighboring gene predicted gene, 52116 Neighboring gene STARR-positive B cell enhancer ABC_E8557 Neighboring gene predicted gene, 26782 Neighboring gene Apex1 promoter region Neighboring gene O-sialoglycoprotein endopeptidase Neighboring gene apurinic/apyrimidinic endonuclease 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    kelch-like protein 33

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001166651.2 → NP_001160123.1  kelch-like protein 33 isoform 2

      See identical proteins and their annotated locations for NP_001160123.1

      Status: INFERRED

      Source sequence(s)
      AC027184
      Consensus CDS
      CCDS56952.1
      UniProtKB/TrEMBL
      G3UW92
      Related
      ENSMUSP00000129810.2, ENSMUST00000164415.2
      Conserved Domains (6) summary
      smart00612
      Location:323 → 369
      Kelch; Kelch domain
      smart00225
      Location:1 → 70
      BTB; Broad-Complex, Tramtrack and Bric a brac
      smart00875
      Location:75 → 175
      BACK; BTB And C-terminal Kelch
      TIGR03547
      Location:253 → 505
      muta_rot_YjhT; mutatrotase, YjhT family
      sd00038
      Location:312 → 355
      Kelch; KELCH repeat [structural motif]
      pfam01344
      Location:358 → 393
      Kelch_1; Kelch motif

    2. NM_001370764.1 → NP_001357693.1  kelch-like protein 33 isoform 1

      Status: INFERRED

      Source sequence(s)
      AC027184
      Consensus CDS
      CCDS88651.1
      UniProtKB/TrEMBL
      A0A2I3BRZ3
      Related
      ENSMUSP00000154785.2, ENSMUST00000227271.2
      Conserved Domains (3) summary
      PHA03098
      Location:319 → 738
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:572 → 615
      Kelch; KELCH repeat [structural motif]
      cl38908
      Location:220 → 337
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      51126038..51134940 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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