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    Rad51ap1 RAD51 associated protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 19362, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rad51ap1provided by MGI
    Official Full Name
    RAD51 associated protein 1provided by MGI
    Primary source
    MGI:MGI:1098224
    See related
    Ensembl:ENSMUSG00000030346
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RAB; RAB22; 2510006L10Rik
    Expression
    Biased expression in liver E14 (RPKM 17.5), liver E14.5 (RPKM 14.3) and 10 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rad51ap1 in Genome Data Viewer
    Location:
    6 F3; 6 61.92 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (126900378..126916664, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (126923415..126939621, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (126873437..126889573, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene A kinase (PRKA) anchor protein 3 Neighboring gene dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 Neighboring gene metaxin 1 pseudogene Neighboring gene DNA segment, Chr 6, Wayne State University 163, expressed Neighboring gene predicted gene 43124

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables D-loop DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA secondary structure binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables double-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables single-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables single-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chromosome, telomeric region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    RAD51-associated protein 1
    Names
    RAD51-interacting protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347455.1NP_001334384.1  RAD51-associated protein 1 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1
      Source sequence(s)
      AK077829, AK079525, AW457762, BB620338
      Consensus CDS
      CCDS85161.1
      UniProtKB/Swiss-Prot
      Q8C551
      UniProtKB/TrEMBL
      A0A0R4J1H1
      Related
      ENSMUSP00000107839.2, ENSMUST00000112220.8
    2. NM_009013.4NP_033039.2  RAD51-associated protein 1 isoform 1

      See identical proteins and their annotated locations for NP_033039.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AK077829, AK079525, AW457762, BB620338
      Consensus CDS
      CCDS39644.1
      UniProtKB/Swiss-Prot
      Q8C551
      UniProtKB/TrEMBL
      A0A0R4J1G4
      Related
      ENSMUSP00000107841.2, ENSMUST00000112221.8
      Conserved Domains (2) summary
      pfam10486
      Location:126268
      PI3K_1B_p101; Phosphoinositide 3-kinase gamma adapter protein p101 subunit
      pfam15696
      Location:293331
      RAD51_interact; RAD51 interacting motif

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      126900378..126916664 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030255239.1XP_030111099.1  RAD51-associated protein 1 isoform X1

      Conserved Domains (2) summary
      pfam10500
      Location:46148
      SR-25; Nuclear RNA-splicing-associated protein
      pfam15696
      Location:193231
      RAD51_interact; RAD51 interacting motif
    2. XM_030255240.1XP_030111100.1  RAD51-associated protein 1 isoform X1

      Conserved Domains (2) summary
      pfam10500
      Location:46148
      SR-25; Nuclear RNA-splicing-associated protein
      pfam15696
      Location:193231
      RAD51_interact; RAD51 interacting motif

    RNA

    1. XR_004942924.1 RNA Sequence

    2. XR_377433.4 RNA Sequence

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