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    Dcbld1 discoidin, CUB and LCCL domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 66686, updated on 23-Jun-2021

    Summary

    Official Symbol
    Dcbld1provided by MGI
    Official Full Name
    discoidin, CUB and LCCL domain containing 1provided by MGI
    Primary source
    MGI:MGI:1913936
    See related
    Ensembl:ENSMUSG00000019891
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4631413K11Rik
    Expression
    Ubiquitous expression in duodenum adult (RPKM 9.1), large intestine adult (RPKM 8.4) and 27 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Dcbld1 in Genome Data Viewer
    Location:
    10; 10 B3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (52109674..52197474)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (52233578..52321378)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (51953425..52041183)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene Ros1 proto-oncogene Neighboring gene predicted gene 20630 Neighboring gene crumbs homolog 1 pseudogene Neighboring gene Ewing sarcoma breakpoint region 1 pseudogene Neighboring gene golgi associated PDZ and coiled-coil motif containing Neighboring gene ribosomal protein S19, pseudogene 10

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in zymogen activation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in blood microparticle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    discoidin, CUB and LCCL domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347444.1NP_001334373.1  discoidin, CUB and LCCL domain-containing protein 1 isoform 2 precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. The encoded isoform (2) has the same N- and C-termini, but is shorter than isoform 1.
      Source sequence(s)
      AC153525, AK014521, AK016485, AV229589, BY096153
      Consensus CDS
      CCDS83696.1
      UniProtKB/Swiss-Prot
      Q9D4J3
      Related
      ENSMUSP00000151265.2, ENSMUST00000218582.2
    2. NM_025705.4NP_079981.2  discoidin, CUB and LCCL domain-containing protein 1 isoform 1 precursor

      See identical proteins and their annotated locations for NP_079981.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC153525, AK014521, AK016485, AV229589, BY096153
      Consensus CDS
      CCDS23839.1
      UniProtKB/Swiss-Prot
      Q9D4J3
      Related
      ENSMUSP00000068203.6, ENSMUST00000069004.14
      Conserved Domains (2) summary
      cd00041
      Location:32140
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cl02694
      Location:147239
      LCCL; LCCL domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      52109674..52197474
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011243196.2XP_011241498.1  discoidin, CUB and LCCL domain-containing protein 1 isoform X1

      Conserved Domains (2) summary
      cd00041
      Location:32140
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cl02694
      Location:165229
      LCCL; LCCL domain
    2. XM_030245220.1XP_030101080.1  discoidin, CUB and LCCL domain-containing protein 1 isoform X2

    3. XM_030245221.2XP_030101081.1  discoidin, CUB and LCCL domain-containing protein 1 isoform X2

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