Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) [ Mus musculus (house mouse) ]

    Gene ID: 16912, updated on 23-Jun-2021

    Summary

    Official Symbol
    Psmb9provided by MGI
    Official Full Name
    proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)provided by MGI
    Primary source
    MGI:MGI:1346526
    See related
    Ensembl:ENSMUSG00000096727
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Lm; Lmp; Lmp2; Lmp-2
    Expression
    Broad expression in large intestine adult (RPKM 97.4), thymus adult (RPKM 90.4) and 16 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Psmb9 in Genome Data Viewer
    Location:
    17 B1; 17 17.98 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (34400961..34406304, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (34182030..34187330, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (34319044..34324275, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene histocompatibility 2, class II, locus Mb2 Neighboring gene histocompatibility 2, class II, locus Mb1 Neighboring gene transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) Neighboring gene proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables proteasome binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables threonine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of proteasome complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of proteasome core complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of proteasome core complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of proteasome core complex, beta-subunit complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of spermatoproteasome complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    proteasome subunit beta type-9
    Names
    LMP-2d
    large multifunctional protease 2
    low molecular mass protein 2
    macropain chain 7
    multicatalytic endopeptidase complex chain 7
    proteasome chain 7
    proteasome subunit beta-1i
    proteosome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
    proteosome beta 9 subunit
    really interesting new gene 12 protein
    NP_038613.1
    XP_006523793.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013585.2NP_038613.1  proteasome subunit beta type-9

      See identical proteins and their annotated locations for NP_038613.1

      Status: VALIDATED

      Source sequence(s)
      CR974422
      Consensus CDS
      CCDS28642.1
      UniProtKB/Swiss-Prot
      P28076
      UniProtKB/TrEMBL
      A0A0R4J256
      Related
      ENSMUSP00000133499.2, ENSMUST00000174576.4
      Conserved Domains (2) summary
      COG0638
      Location:13219
      PRE1; 20S proteasome, alpha and beta subunits [Posttranslational modification, protein turnover, chaperones]
      cd03762
      Location:21207
      proteasome_beta_type_6; proteasome beta type-6 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      34400961..34406304 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006523730.4XP_006523793.1  proteasome subunit beta type-9 isoform X1

      See identical proteins and their annotated locations for XP_006523793.1

      Conserved Domains (1) summary
      cd03762
      Location:1184
      proteasome_beta_type_6; proteasome beta type-6 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...
    Support Center