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    Plcxd2 phosphatidylinositol-specific phospholipase C, X domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 433022, updated on 21-Apr-2024

    Summary

    Official Symbol
    Plcxd2provided by MGI
    Official Full Name
    phosphatidylinositol-specific phospholipase C, X domain containing 2provided by MGI
    Primary source
    MGI:MGI:3647874
    See related
    Ensembl:ENSMUSG00000087141 AllianceGenome:MGI:3647874
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EG433022
    Summary
    Predicted to enable phosphoric diester hydrolase activity. Predicted to be involved in lipid metabolic process. Predicted to act upstream of or within lipid catabolic process and signal transduction. Predicted to be located in nucleus. Is expressed in alimentary system; limb; liver; nervous system; and retina. Orthologous to human PLCXD2 (phosphatidylinositol specific phospholipase C X domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in cerebellum adult (RPKM 12.6), cortex adult (RPKM 10.3) and 17 other tissues See more
    Orthologs
    NEW
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    Genomic context

    Location:
    16 B5; 16 30.45 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (45779624..45830776, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (45959261..46010413, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_40921 Neighboring gene abhydrolase domain containing 10 Neighboring gene pleckstrin homology like domain, family B, member 2 Neighboring gene STARR-seq mESC enhancer starr_40922 Neighboring gene predicted gene 15638 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:46006394-46006690 Neighboring gene STARR-positive B cell enhancer ABC_E4173 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:46011002-46011185 Neighboring gene predicted gene, 24754 Neighboring gene predicted gene, 31198

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (2) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    enables phosphoric diester hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    acts_upstream_of_or_within lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    PI-PLC X domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134480.1NP_001127952.1  PI-PLC X domain-containing protein 2

      See identical proteins and their annotated locations for NP_001127952.1

      Status: VALIDATED

      Source sequence(s)
      BC049364, BC151059, CJ104359
      Consensus CDS
      CCDS49863.1
      UniProtKB/Swiss-Prot
      B2RXA1
      Related
      ENSMUSP00000114852.2, ENSMUST00000130481.2
      Conserved Domains (1) summary
      cd08616
      Location:39329
      PI-PLCXD1c; Catalytic domain of phosphatidylinositol-specific phospholipase C, X domain containing 1

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      45779624..45830776 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)