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    Rccd1 RCC1 domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 269955, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Rccd1provided by MGI
    Official Full Name
    RCC1 domain containing 1provided by MGI
    Primary source
    MGI:MGI:2444156
    See related
    Ensembl:ENSMUSG00000038930 AllianceGenome:MGI:2444156
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    5830436H09; E430018M08Rik
    Summary
    Predicted to act upstream of or within chromatin organization. Predicted to be located in cytosol and plasma membrane. Is expressed in central nervous system; gonad; metanephros; and vascular system. Orthologous to human RCCD1 (RCC1 domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E14 (RPKM 4.7), CNS E11.5 (RPKM 4.2) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    7 D2; 7 45.64 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (79944339..79974512, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (80294591..80324687, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E2826 Neighboring gene neugrin, neurite outgrowth associated Neighboring gene vacuolar protein sorting 33B Neighboring gene STARR-positive B cell enhancer ABC_E2827 Neighboring gene protein regulator of cytokinesis 1 Neighboring gene unc-45 myosin chaperone A Neighboring gene STARR-positive B cell enhancer ABC_E2828 Neighboring gene STARR-positive B cell enhancer ABC_E6566 Neighboring gene HD domain containing 3 Neighboring gene high mobility group box 2 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA. Liu X, et al. BMC Immunol, 2016 Aug 2. PMID 27480124, Free PMC Article
    2. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
    3. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    acts_upstream_of_or_within chromatin organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    RCC1 domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173445.4 → NP_775621.2  RCC1 domain-containing protein 1

      See identical proteins and their annotated locations for NP_775621.2

      Status: VALIDATED

      Source sequence(s)
      AC136740, AK030872, AK088482, BM218704
      Consensus CDS
      CCDS21394.1
      UniProtKB/Swiss-Prot
      Q6IS64, Q8BJF2, Q8BTU7, Q8C0K3
      Related
      ENSMUSP00000048043.5, ENSMUST00000047362.11
      Conserved Domains (1) summary
      COG5184
      Location:159 → 341
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      79944339..79974512 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017322294.3 → XP_017177783.1  RCC1 domain-containing protein 1 isoform X1

      UniProtKB/Swiss-Prot
      Q6IS64, Q8BJF2, Q8BTU7, Q8C0K3
      Conserved Domains (1) summary
      COG5184
      Location:159 → 341
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]

    2. XM_006540928.4 → XP_006540991.1  RCC1 domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006540991.1

      UniProtKB/Swiss-Prot
      Q6IS64, Q8BJF2, Q8BTU7, Q8C0K3
      Conserved Domains (1) summary
      COG5184
      Location:159 → 341
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]

    3. XM_006540926.4 → XP_006540989.1  RCC1 domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006540989.1

      UniProtKB/Swiss-Prot
      Q6IS64, Q8BJF2, Q8BTU7, Q8C0K3
      Conserved Domains (1) summary
      COG5184
      Location:159 → 341
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]

    4. XM_006540930.5 → XP_006540993.1  RCC1 domain-containing protein 1 isoform X3

      Conserved Domains (2) summary
      COG5184
      Location:41 → 162
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      pfam00415
      Location:147 → 190
      RCC1; Regulator of chromosome condensation (RCC1) repeat

    5. XM_006540929.4 → XP_006540992.1  RCC1 domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006540992.1

      UniProtKB/Swiss-Prot
      Q6IS64, Q8BJF2, Q8BTU7, Q8C0K3
      Conserved Domains (1) summary
      COG5184
      Location:159 → 341
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]

    6. XM_036153143.1 → XP_036009036.1  RCC1 domain-containing protein 1 isoform X2

      Conserved Domains (2) summary
      pfam00415
      Location:180 → 228
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam13540
      Location:163 → 192
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat

    RNA

    1. XR_882031.4 RNA Sequence

    2. XR_004934113.1 RNA Sequence

    3. XR_004934114.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BTU7.2 GenPept UniProtKB/Swiss-Prot:Q8BTU7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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