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    Zfp438 zinc finger protein 438 [ Mus musculus (house mouse) ]

    Gene ID: 240186, updated on 23-Jun-2021

    Summary

    Official Symbol
    Zfp438provided by MGI
    Official Full Name
    zinc finger protein 438provided by MGI
    Primary source
    MGI:MGI:2444919
    See related
    Ensembl:ENSMUSG00000050945
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9430031G09; 9430091M14Rik; B830013J05Rik
    Expression
    Broad expression in testis adult (RPKM 12.1), bladder adult (RPKM 1.5) and 17 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Zfp438 in Genome Data Viewer
    Location:
    18; 18 A1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (5210027..5334826, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (5210027..5334826, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (5210029..5334437, complement)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53196 Neighboring gene predicted gene, 26682 Neighboring gene predicted gene, 52372 Neighboring gene predicted gene, 34630

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360447.1NP_001347376.1  zinc finger protein 438

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC111128, AC133945
      Consensus CDS
      CCDS37721.1
      Related
      ENSMUSP00000156983.2, ENSMUST00000234241.2
      Conserved Domains (3) summary
      sd00017
      Location:495515
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:521543
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:507532
      zf-H2C2_2; Zinc-finger double domain
    2. NM_178722.5NP_848837.3  zinc finger protein 438

      See identical proteins and their annotated locations for NP_848837.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK034745, AK046812
      Consensus CDS
      CCDS37721.1
      UniProtKB/TrEMBL
      Q8BFX2, Q8BXJ4
      Related
      ENSMUSP00000067049.6, ENSMUST00000063989.7
      Conserved Domains (3) summary
      sd00017
      Location:495515
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:521543
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:507532
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      5210027..5334826 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036161137.1XP_036017030.1  zinc finger protein 438 isoform X2

      Conserved Domains (2) summary
      sd00017
      Location:430450
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:456478
      zf-C2H2; Zinc finger, C2H2 type
    2. XM_011246916.2XP_011245218.1  zinc finger protein 438 isoform X1

      See identical proteins and their annotated locations for XP_011245218.1

      UniProtKB/TrEMBL
      Q8BFX2
      Conserved Domains (3) summary
      sd00017
      Location:495515
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:521543
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:507532
      zf-H2C2_2; Zinc-finger double domain
    3. XM_036161136.1XP_036017029.1  zinc finger protein 438 isoform X2

      Conserved Domains (2) summary
      sd00017
      Location:430450
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:456478
      zf-C2H2; Zinc finger, C2H2 type
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