Imp4 IMP4, U3 small nucleolar ribonucleoprotein [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Imp4provided by MGI
Official Full Name: IMP4, U3 small nucleolar ribonucleoproteinprovided by MGI
Primary source: MGI:MGI:106572
See related: Ensembl:ENSMUSG00000026127 AllianceGenome:MGI:106572
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: D1Wsu40e
Summary: Predicted to enable snoRNA binding activity. Predicted to be involved in rRNA processing. Predicted to act upstream of or within ribosome biogenesis. Predicted to be located in fibrillar center. Predicted to be part of Mpp10 complex and small-subunit processome. Predicted to be active in nucleolus. Is expressed in several structures, including axial musculature; extraembryonic component; submandibular gland primordium; thymus primordium; and vibrissa. Orthologous to human IMP4 (IMP U3 small nucleolar ribonucleoprotein 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in thymus adult (RPKM 19.3), ovary adult (RPKM 18.6) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 1 B; 1 13.22 cM

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	1	NC_000067.7 (34478951..34488437)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	1	NC_000067.6 (34439829..34445747)

Chromosome 1 - NC_000067.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH124901 (e-PCR)
- UniSTS:161723

RH125719 (e-PCR)
- UniSTS:142284

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables rRNA binding	IEA Inferred from Electronic Annotation more info
enables rRNA primary transcript binding	IEA Inferred from Electronic Annotation more info
enables snoRNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in rRNA processing	IBA Inferred from Biological aspect of Ancestor more info
involved_in ribosomal small subunit biogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within ribosome biogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of Mpp10 complex	IBA Inferred from Biological aspect of Ancestor more info
part_of Mpp10 complex	ISO Inferred from Sequence Orthology more info
located_in fibrillar center	ISO Inferred from Sequence Orthology more info
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of preribosome	ISO Inferred from Sequence Orthology more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
part_of small-subunit processome	IBA Inferred from Biological aspect of Ancestor more info
part_of small-subunit processome	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: U3 small nucleolar ribonucleoprotein protein IMP4

Names: IMP4, U3 small nucleolar ribonucleoprotein, homolog; U3 snoRNP protein 4 homolog; U3 snoRNP protein IMP4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001420705.1 → NP_001407634.1 U3 small nucleolar ribonucleoprotein protein IMP4 isoform 2

Status: VALIDATED

Source sequence(s)

AC106841
NM_178601.4 → NP_848716.2 U3 small nucleolar ribonucleoprotein protein IMP4 isoform 1

See identical proteins and their annotated locations for NP_848716.2

Status: VALIDATED

Source sequence(s)

AC106841

Consensus CDS

CCDS35536.1

UniProtKB/Swiss-Prot

Q3U8H6, Q8CI42, Q8VHZ7, Q9CWN6, Q9CYT5

Related

ENSMUSP00000027303.8, ENSMUST00000027303.14

Conserved Domains (1) summary

smart00879
Location:86 → 253

Brix; The Brix domain is found in a number of eukaryotic proteins