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    Katnbl1 katanin p80 subunit B like 1 [ Mus musculus (house mouse) ]

    Gene ID: 72425, updated on 5-Mar-2024

    Summary

    Official Symbol
    Katnbl1provided by MGI
    Official Full Name
    katanin p80 subunit B like 1provided by MGI
    Primary source
    MGI:MGI:1919675
    See related
    Ensembl:ENSMUSG00000027132 AllianceGenome:MGI:1919675
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2410042D21Rik
    Summary
    Predicted to enable microtubule binding activity. Predicted to be involved in positive regulation of cytoskeleton organization. Predicted to be located in several cellular components, including cleavage furrow; midbody; and mitotic spindle pole. Predicted to be active in nucleolus. Orthologous to human KATNBL1 (katanin regulatory subunit B1 like 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in placenta adult (RPKM 7.4), limb E14.5 (RPKM 6.3) and 20 other tissues See more
    Orthologs
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    Genomic context

    Location:
    2 E3; 2 57.02 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (112209556..112244582)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (112379211..112414237)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene solute carrier family 12, member 6 Neighboring gene predicted gene, 39908 Neighboring gene STARR-positive B cell enhancer mm9_chr2:112219168-112219469 Neighboring gene ER membrane protein complex subunit 4 Neighboring gene STARR-positive B cell enhancer ABC_E5959 Neighboring gene STARR-positive B cell enhancer ABC_E3389 Neighboring gene STARR-positive B cell enhancer ABC_E11150 Neighboring gene STARR-positive B cell enhancer ABC_E4487 Neighboring gene ER membrane protein complex subunit 7 Neighboring gene STARR-seq mESC enhancer starr_05388 Neighboring gene cholinergic receptor, muscarinic 5 Neighboring gene predicted gene, 22676 Neighboring gene apoptosis, caspase activation inhibitor

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in cytoplasmic microtubule organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cleavage furrow ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    part_of katanin complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in midbody ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitotic spindle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitotic spindle pole ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024254.3NP_077216.1  KATNB1-like protein 1

      See identical proteins and their annotated locations for NP_077216.1

      Status: PROVISIONAL

      Source sequence(s)
      AL683897
      Consensus CDS
      CCDS16554.1
      UniProtKB/Swiss-Prot
      Q3U7P7, Q8C7R6, Q9CWJ3
      Related
      ENSMUSP00000028552.4, ENSMUST00000028552.4
      Conserved Domains (1) summary
      pfam13925
      Location:148291
      Katanin_con80; con80 domain of Katanin

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      112209556..112244582
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)