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    Fam228b family with sequence similarity 228, member B [ Mus musculus (house mouse) ]

    Gene ID: 207921, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Fam228bprovided by MGI
    Official Full Name
    family with sequence similarity 228, member Bprovided by MGI
    Primary source
    MGI:MGI:2442121
    See related
    Ensembl:ENSMUSG00000050545 AllianceGenome:MGI:2442121
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A830093I24Rik
    Summary
    Orthologous to human FAM228B (family with sequence similarity 228 member B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in testis adult (RPKM 3.8), frontal lobe adult (RPKM 1.5) and 15 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    12 A1.1; 12 2.09 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (4789888..4819259, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (4739888..4769267, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene intersectin 2 Neighboring gene predicted gene, 53750 Neighboring gene family with sequence similarity 228, member A Neighboring gene predicted gene, 23676 Neighboring gene predicted gene, 22003 Neighboring gene profilin family, member 4 Neighboring gene tubulin, alpha 1C pseudogene Neighboring gene quinone oxidoreductase PIG3 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM228B
    Names
    UPF0638 protein B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001382825.1 → NP_001369754.1  protein FAM228B isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (a).
      Source sequence(s)
      CT025683

    2. NM_001382826.1 → NP_001369755.1  protein FAM228B isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2), as well as variant 3, encodes isoform b.
      Source sequence(s)
      CT025683
      UniProtKB/Swiss-Prot
      Q497Q6, Q8BLM3, Q8BWN5

    3. NM_001382827.1 → NP_001369756.1  protein FAM228B isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4), as well as variant 5, encodes isoform c.
      Source sequence(s)
      CT025683
      UniProtKB/TrEMBL
      A0A1W2P7H1

    4. NM_001382828.1 → NP_001369757.1  protein FAM228B isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5), as well as variant 4, encodes isoform c.
      Source sequence(s)
      CT025683
      UniProtKB/TrEMBL
      A0A1W2P7H1
      Related
      ENSMUSP00000151649.2, ENSMUST00000218199.2

    5. NM_001382829.1 → NP_001369758.1  protein FAM228B isoform d

      Status: VALIDATED

      Source sequence(s)
      CT025683

    6. NM_001382830.1 → NP_001369759.1  protein FAM228B isoform e

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7), as well as variant 8, encodes isoform e.
      Source sequence(s)
      CT025683

    7. NM_001382831.1 → NP_001369760.1  protein FAM228B isoform e

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8), as well as variant 7, encodes isoform e.
      Source sequence(s)
      CT025683

    8. NM_001382832.1 → NP_001369761.1  protein FAM228B isoform f

      Status: VALIDATED

      Source sequence(s)
      CT025683

    9. NM_175431.5 → NP_780640.2  protein FAM228B isoform b

      See identical proteins and their annotated locations for NP_780640.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3), as well as variant 2, encodes isoform b.
      Source sequence(s)
      CT025683
      Consensus CDS
      CCDS36400.1
      UniProtKB/Swiss-Prot
      Q497Q6, Q8BLM3, Q8BWN5
      Related
      ENSMUSP00000050881.6, ENSMUST00000053458.7

    RNA

    1. NR_168577.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      CT025683

    2. NR_168578.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      CT025683

    3. NR_168579.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      CT025683

    4. NR_168580.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      CT025683

    5. NR_168581.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      CT025683

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      4789888..4819259 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006515030.2 → XP_006515093.1  protein FAM228B isoform X1

      See identical proteins and their annotated locations for XP_006515093.1

    2. XM_036157291.1 → XP_036013184.1  protein FAM228B isoform X3

    3. XM_036157290.1 → XP_036013183.1  protein FAM228B isoform X2

    4. XM_036157292.1 → XP_036013185.1  protein FAM228B isoform X3

    5. XM_036157289.1 → XP_036013182.1  protein FAM228B isoform X2

    6. XM_030246633.2 → XP_030102493.1  protein FAM228B isoform X5

    7. XM_030246631.2 → XP_030102491.1  protein FAM228B isoform X1

    8. XM_030246634.2 → XP_030102494.1  protein FAM228B isoform X7

    9. XM_036157294.1 → XP_036013187.1  protein FAM228B isoform X6

      Related
      ENSMUSP00000151270.2, ENSMUST00000218575.2

    10. XM_036157293.1 → XP_036013186.1  protein FAM228B isoform X4

    RNA

    1. XR_004937472.1 RNA Sequence

    2. XR_004937475.1 RNA Sequence

    3. XR_004937477.1 RNA Sequence

    4. XR_004937478.1 RNA Sequence

    5. XR_004937476.1 RNA Sequence

    6. XR_004937473.1 RNA Sequence

    7. XR_003950021.2 RNA Sequence

    8. XR_004937471.1 RNA Sequence

    9. XR_004937470.1 RNA Sequence

    10. XR_004937474.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q497Q6.1 GenPept UniProtKB/Swiss-Prot:Q497Q6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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