Lrif1 ligand dependent nuclear receptor interacting factor 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Lrif1provided by RGD
Official Full Name: ligand dependent nuclear receptor interacting factor 1provided by RGD
Primary source: RGD:1306520
See related: Ensembl:ENSRNOG00000017784 AllianceGenome:RGD:1306520
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1306520
Summary: Predicted to enable retinoic acid receptor binding activity. Predicted to be involved in dosage compensation by inactivation of X chromosome. Predicted to be located in Barr body; centriolar satellite; and nucleoplasm. Predicted to colocalize with chromosome, telomeric region. Orthologous to human LRIF1 (ligand dependent nuclear receptor interacting factor 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Testes (RPKM 92.7), Thymus (RPKM 80.4) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 2q34

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (196919606..197010713)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (194231397..194322489)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (209358668..209448123)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables nuclear retinoic acid receptor binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in dosage compensation by inactivation of X chromosome	IEA Inferred from Electronic Annotation more info
involved_in dosage compensation by inactivation of X chromosome	ISO Inferred from Sequence Orthology more info
involved_in dosage compensation by inactivation of X chromosome	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Barr body	IEA Inferred from Electronic Annotation more info
located_in Barr body	ISO Inferred from Sequence Orthology more info
located_in Barr body	ISS Inferred from Sequence or Structural Similarity more info
located_in centriolar satellite	IEA Inferred from Electronic Annotation more info
located_in centriolar satellite	ISO Inferred from Sequence Orthology more info
located_in chromosome, telomeric region	IEA Inferred from Electronic Annotation more info
located_in chromosome, telomeric region	ISO Inferred from Sequence Orthology more info
located_in nuclear matrix	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: ligand-dependent nuclear receptor-interacting factor 1

Names: receptor interacting factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001127485.1 → NP_001120957.1 ligand-dependent nuclear receptor-interacting factor 1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000002

UniProtKB/Swiss-Prot

Q499M7

UniProtKB/TrEMBL

F1LMD4

Related

ENSRNOP00000024036.5, ENSRNOT00000024036.6

Conserved Domains (1) summary

pfam15741
Location:26 → 747

LRIF1; Ligand-dependent nuclear receptor-interacting factor 1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086020.1 Reference GRCr8

Range

196919606..197010713

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006233147.5 → XP_006233209.1 ligand-dependent nuclear receptor-interacting factor 1 isoform X2

UniProtKB/TrEMBL

A0A0G2JZ59, B0BNF2

Related

ENSRNOP00000070919.2

Conserved Domains (1) summary

pfam15741
Location:17 → 252

LRIF1; Ligand-dependent nuclear receptor-interacting factor 1
XM_039102422.2 → XP_038958350.1 ligand-dependent nuclear receptor-interacting factor 1 isoform X1

UniProtKB/TrEMBL

A6HUR4

Conserved Domains (1) summary

pfam15741
Location:26 → 511

LRIF1; Ligand-dependent nuclear receptor-interacting factor 1