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    Retreg2 reticulophagy regulator family member 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363252, updated on 13-Apr-2024

    Summary

    Official Symbol
    Retreg2provided by RGD
    Official Full Name
    reticulophagy regulator family member 2provided by RGD
    Primary source
    RGD:1306844
    See related
    Ensembl:ENSRNOG00000018586 AllianceGenome:RGD:1306844
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam134a; RGD1306844
    Summary
    Predicted to be integral component of membrane. Orthologous to human RETREG2 (reticulophagy regulator family member 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 279.4), Kidney (RPKM 142.6) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Retreg2 in Genome Data Viewer
    Location:
    9q33
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (84088935..84095072)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (76640282..76646400)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (82345686..82351800)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 23, member 3 Neighboring gene cyclin Pas1/PHO80 domain containing 1 Neighboring gene zinc finger AN1-type containing 2B Neighboring gene ATP binding cassette subfamily B member 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables endoplasmic reticulum-autophagosome adaptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables endoplasmic reticulum-autophagosome adaptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in collagen catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within collagen catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endoplasmic reticulum organization IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within endoplasmic reticulum organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in reticulophagy IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within reticulophagy ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    reticulophagy regulator 2
    Names
    family with sequence similarity 134, member A
    protein FAM134A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100760.1NP_001094230.1  reticulophagy regulator 2

      See identical proteins and their annotated locations for NP_001094230.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/Swiss-Prot
      Q3MHU5
      UniProtKB/TrEMBL
      A0A8L2UMN5, A6JVX7
      Related
      ENSRNOP00000054145.3, ENSRNOT00000057330.5

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      84088935..84095072
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006245244.5XP_006245306.1  reticulophagy regulator 2 isoform X1

      See identical proteins and their annotated locations for XP_006245306.1

      UniProtKB/TrEMBL
      A0A0G2K1U5, A0A8L2UMN5, A6JVX8
      Related
      ENSRNOP00000071987.2
    2. XM_017596525.2XP_017452014.1  reticulophagy regulator 2 isoform X2

      UniProtKB/TrEMBL
      A6JVX9