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    Vps26b VPS26 retromer complex component B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 300472, updated on 25-Apr-2024

    Summary

    Official Symbol
    Vps26bprovided by RGD
    Official Full Name
    VPS26 retromer complex component Bprovided by RGD
    Primary source
    RGD:1597170
    See related
    Ensembl:ENSRNOG00000047235 AllianceGenome:RGD:1597170
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in intracellular protein transport and retrograde transport, endosome to Golgi. Predicted to act upstream of or within cellular response to interferon-gamma. Predicted to be located in early endosome; late endosome; and phagocytic vesicle. Predicted to be part of retromer complex. Predicted to be active in endosome. Orthologous to human VPS26B (VPS26, retromer complex component B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Heart (RPKM 190.4), Brain (RPKM 181.2) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Vps26b in Genome Data Viewer
    Location:
    8q13
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (33675025..33696132, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (25415877..25436985, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (28054407..28075514, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene acyl-CoA dehydrogenase family, member 8 Neighboring gene thymocyte nuclear protein 1 Neighboring gene non-SMC condensin II complex, subunit D3 Neighboring gene uncharacterized LOC134480003 Neighboring gene junctional adhesion molecule 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in early endosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in late endosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in phagocytic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in postsynaptic early endosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in postsynaptic recycling endosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of retromer complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of retromer complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    vacuolar protein sorting-associated protein 26B
    Names
    vacuolar protein sorting 26 homolog B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106809.1NP_001100279.1  vacuolar protein sorting-associated protein 26B

      See identical proteins and their annotated locations for NP_001100279.1

      Status: VALIDATED

      Source sequence(s)
      BC161865, CA334760, CA339357, CB578687, CF113332, CO394403, EV779065
      UniProtKB/TrEMBL
      B1WBS4, M0R4K2
      Related
      ENSRNOP00000064289.1, ENSRNOT00000072851.2
      Conserved Domains (1) summary
      pfam03643
      Location:6281
      Vps26; Vacuolar protein sorting-associated protein 26

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      33675025..33696132 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)