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    Tmem9b TMEM9 domain family, member B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293415, updated on 13-Apr-2024

    Summary

    Official Symbol
    Tmem9bprovided by RGD
    Official Full Name
    TMEM9 domain family, member Bprovided by RGD
    Primary source
    RGD:1310775
    See related
    Ensembl:ENSRNOG00000069185 AllianceGenome:RGD:1310775
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310775
    Summary
    Predicted to be involved in positive regulation of I-kappaB kinase/NF-kappaB signaling. Predicted to be located in lysosomal membrane. Predicted to be integral component of membrane. Orthologous to human TMEM9B (TMEM9 domain family member B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 136.9), Kidney (RPKM 116.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tmem9b in Genome Data Viewer
    Location:
    1q33
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (173199225..173218674, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (163755307..163783880, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (174360533..174380326, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene A-kinase interacting protein 1 Neighboring gene similar to human chromosome 11 open reading frame 16 Neighboring gene achaete-scute family bHLH transcription factor 3 Neighboring gene uncharacterized LOC134483769 Neighboring gene nuclear receptor interacting protein 3 Neighboring gene uncharacterized LOC134483771

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106289.2NP_001099759.1  transmembrane protein 9B isoform 2

      See identical proteins and their annotated locations for NP_001099759.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A6I7Z0
      Conserved Domains (1) summary
      pfam05434
      Location:1123
      Tmemb_9; TMEM9
    2. NM_001398743.1NP_001385672.1  transmembrane protein 9B isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A6I7Y9, D3ZW49
      Related
      ENSRNOP00000063402.2, ENSRNOT00000067388.2
      Conserved Domains (1) summary
      pfam05434
      Location:58198
      Tmemb_9; TMEM9

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      173199225..173218674 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)