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    Slc25a45 solute carrier family 25, member 45 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 689625, updated on 13-Apr-2024

    Summary

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    Official Symbol
    Slc25a45provided by RGD
    Official Full Name
    solute carrier family 25, member 45provided by RGD
    Primary source
    RGD:1589953
    See related
    Ensembl:ENSRNOG00000030616 AllianceGenome:RGD:1589953
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable acyl carnitine transmembrane transporter activity. Predicted to be involved in acyl carnitine transport and amino acid transport. Predicted to be integral component of membrane. Orthologous to human SLC25A45 (solute carrier family 25 member 45). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 200.5), Liver (RPKM 45.5) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    1q43
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (212595536..212603786)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (203166362..203174473)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (221236817..221244564)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120097382 Neighboring gene uncharacterized LOC120097381 Neighboring gene FERM domain containing 8 Neighboring gene U2 spliceosomal RNA Neighboring gene tigger transposable element derived 3 Neighboring gene double PHD fingers 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    solute carrier family 25 member 45

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001271179.1 → NP_001258108.1  solute carrier family 25 member 45

      See identical proteins and their annotated locations for NP_001258108.1

      Status: VALIDATED

      Source sequence(s)
      FM090288, JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I6GJ25, A6HZA7, D3ZL04
      Related
      ENSRNOP00000041281.4, ENSRNOT00000051979.6
      Conserved Domains (1) summary
      pfam00153
      Location:197 → 288
      Mito_carr; Mitochondrial carrier protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      212595536..212603786
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063274640.1 → XP_063130710.1  solute carrier family 25 member 45 isoform X2

    2. XM_039091371.2 → XP_038947299.1  solute carrier family 25 member 45 isoform X2

      UniProtKB/TrEMBL
      A0A8I6GJ25
      Conserved Domains (1) summary
      pfam00153
      Location:139 → 230
      Mito_carr; Mitochondrial carrier protein

    3. XM_039091368.2 → XP_038947296.1  solute carrier family 25 member 45 isoform X2

      UniProtKB/TrEMBL
      A0A8I6GJ25
      Conserved Domains (1) summary
      pfam00153
      Location:139 → 230
      Mito_carr; Mitochondrial carrier protein

    4. XM_008760179.4 → XP_008758401.1  solute carrier family 25 member 45 isoform X1

      UniProtKB/TrEMBL
      A0A8I6GJ25
      Conserved Domains (1) summary
      pfam00153
      Location:201 → 292
      Mito_carr; Mitochondrial carrier protein

    5. XM_039091381.2 → XP_038947309.1  solute carrier family 25 member 45 isoform X3

      Conserved Domains (1) summary
      pfam00153
      Location:63 → 154
      Mito_carr; Mitochondrial carrier protein
    Nucleotide Protein Strain
    Heading Accession and Version

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