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    Hycc2 hyccin PI4KA lipid kinase complex subunit 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 316415, updated on 3-Apr-2024

    Summary

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    Official Symbol
    Hycc2provided by RGD
    Official Full Name
    hyccin PI4KA lipid kinase complex subunit 2provided by RGD
    Primary source
    RGD:1309752
    See related
    Ensembl:ENSRNOG00000025079 AllianceGenome:RGD:1309752
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam126b; RGD1309752
    Summary
    Predicted to be involved in phosphatidylinositol phosphate biosynthetic process and protein localization to plasma membrane. Predicted to be located in cytosol. Predicted to be active in plasma membrane. Orthologous to human FAM126B (family with sequence similarity 126 member B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 204.8), Kidney (RPKM 156.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    9q31
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (67551064..67623353, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (60056883..60129176, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (65406136..65478399, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene U2 spliceosomal RNA Neighboring gene NGG1 interacting factor 3 like 1 Neighboring gene origin recognition complex, subunit 2 Neighboring gene BAF nuclear assembly factor 1, pseudogene 3 Neighboring gene NADH:ubiquinone oxidoreductase subunit B3 Neighboring gene uncharacterized LOC100909946 Neighboring gene CASP8 and FADD-like apoptosis regulator

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC116143

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in phosphatidylinositol phosphate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein localization to plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    hyccin 2
    Names
    family with sequence similarity 126, member B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025710.2 → NP_001020881.2  hyccin 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A0A8I6A5B0, A6IP75
      Conserved Domains (1) summary
      pfam09790
      Location:22 → 330
      Hyccin

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      67551064..67623353 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006244984.4 → XP_006245046.1  hyccin 2 isoform X3

      See identical proteins and their annotated locations for XP_006245046.1

      UniProtKB/TrEMBL
      A0A8I6A5B0, A6IP75
      Related
      ENSRNOP00000087875.1, ENSRNOT00000098396.1
      Conserved Domains (1) summary
      pfam09790
      Location:22 → 330
      Hyccin

    2. XM_006244983.4 → XP_006245045.1  hyccin 2 isoform X2

      See identical proteins and their annotated locations for XP_006245045.1

      UniProtKB/TrEMBL
      A0A8I5ZT89, A6IP75
      Related
      ENSRNOP00000082000.1, ENSRNOT00000118168.1
      Conserved Domains (1) summary
      pfam09790
      Location:22 → 330
      Hyccin

    3. XM_017596454.2 → XP_017451943.1  hyccin 2 isoform X1

      UniProtKB/TrEMBL
      A6IP75
      Conserved Domains (2) summary
      PHA03307
      Location:306 → 487
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam09790
      Location:22 → 330
      Hyccin

    4. XM_017596455.3 → XP_017451944.1  hyccin 2 isoform X1

      UniProtKB/TrEMBL
      A6IP75
      Conserved Domains (2) summary
      PHA03307
      Location:306 → 487
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam09790
      Location:22 → 330
      Hyccin

    5. XM_039083620.2 → XP_038939548.1  hyccin 2 isoform X1

      UniProtKB/TrEMBL
      A6IP75
      Conserved Domains (2) summary
      PHA03307
      Location:306 → 487
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam09790
      Location:22 → 330
      Hyccin

    6. XM_063267184.1 → XP_063123254.1  hyccin 2 isoform X3

      UniProtKB/TrEMBL
      A0A8I6A5B0

    7. XM_063267185.1 → XP_063123255.1  hyccin 2 isoform X3

      UniProtKB/TrEMBL
      A0A8I6A5B0

    8. XM_063267186.1 → XP_063123256.1  hyccin 2 isoform X3

      UniProtKB/TrEMBL
      A0A8I6A5B0

    9. XM_017596458.3 → XP_017451947.1  hyccin 2 isoform X1

      UniProtKB/TrEMBL
      A6IP75
      Conserved Domains (2) summary
      PHA03307
      Location:306 → 487
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam09790
      Location:22 → 330
      Hyccin

    10. XM_063267187.1 → XP_063123257.1  hyccin 2 isoform X5

    11. XM_039083623.2 → XP_038939551.1  hyccin 2 isoform X4

      Conserved Domains (1) summary
      pfam09790
      Location:22 → 330
      Hyccin
    Nucleotide Protein Strain
    Heading Accession and Version

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