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    Nynrin NYN domain and retroviral integrase containing [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100912447, updated on 8-Mar-2024

    Summary

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    Official Symbol
    Nynrinprovided by RGD
    Official Full Name
    NYN domain and retroviral integrase containingprovided by RGD
    Primary source
    RGD:6486974
    See related
    Ensembl:ENSRNOG00000048431 AllianceGenome:RGD:6486974
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in DNA integration. Orthologous to human NYNRIN (NYN domain and retroviral integrase containing). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Lung (RPKM 64.6), Kidney (RPKM 47.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Nynrin in Genome Data Viewer
    Location:
    15p13
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (33302778..33325120)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (29332873..29355215)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (34520040..34541671)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene adenylate cyclase 4 Neighboring gene receptor-interacting serine-threonine kinase 3 Neighboring gene nuclear factor of activated T-cells 4 Neighboring gene cerebellin 3 precursor Neighboring gene KH and NYN domain containing Neighboring gene short chain dehydrogenase/reductase family 39U, member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA-DNA hybrid ribonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA integration IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein NYNRIN
    Names
    protein NYNRIN-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      33302778..33325120
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039093836.2 → XP_038949764.1  protein NYNRIN

      UniProtKB/TrEMBL
      M0RAC3
      Related
      ENSRNOP00000066468.3
      Conserved Domains (6) summary
      cd18728
      Location:802 → 926
      PIN_N4BP1-like; PRORP-like PIN domain of NEDD4 binding protein 1 and related proteins
      pfam17919
      Location:1136 → 1236
      RT_RNaseH_2; RNase H-like domain found in reverse transcriptase
      pfam17921
      Location:1542 → 1599
      Integrase_H2C2; Integrase zinc binding domain
      NF033913
      Location:545 → 692
      fibronec_FbpA; LPXTG-anchored fibronectin-binding protein FbpA
      cd09032
      Location:12 → 73
      KH-I_N4BP1_like_rpt1; first type I K homology (KH) RNA-binding domain found in the family of NEDD4-binding protein 1 (N4BP1)
      cd22477
      Location:75 → 140
      KH-I_NYNRIN_like; type I K homology (KH) RNA-binding domain found in the subfamily of NYN domain and retroviral integrase catalytic domain-containing protein (NYNRIN)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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