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    Ifi44l interferon-induced protein 44-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 310968, updated on 13-Apr-2024

    Summary

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    Official Symbol
    Ifi44lprovided by RGD
    Official Full Name
    interferon-induced protein 44-likeprovided by RGD
    Primary source
    RGD:1595861
    See related
    Ensembl:ENSRNOG00000049994 AllianceGenome:RGD:1595861
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    H28
    Summary
    Predicted to enable GTP binding activity. Predicted to be involved in defense response to virus and immune response. Predicted to be located in cytoplasm. Orthologous to human IFI44L (interferon induced protein 44 like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 252.7), Spleen (RPKM 208.1) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    2q45
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (243328629..243366404)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (240668742..240706425)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (256948722..256979573)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102548445 Neighboring gene interferon-induced protein 44 Neighboring gene prostaglandin F receptor Neighboring gene proteasome maturation protein pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Differences that matter: major cytotoxic T cell-stimulating minor histocompatibility antigens. Malarkannan S, et al. Immunity, 2000 Sep. PMID 11021531
    2. A diverse range of gene products are effectors of the type I interferon antiviral response. Schoggins JW, et al. Nature, 2011 Apr 28. PMID 21478870, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in defense response to virus IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within immune response ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    interferon-induced protein 44-like
    Names
    histocompatibility 28

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427160.1 → NP_001414089.1  interferon-induced protein 44-like

      Status: INFERRED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A0A8I6AEX3

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      243328629..243366404
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_227820.10 → XP_227820.6  interferon-induced protein 44-like isoform X1

      UniProtKB/TrEMBL
      M0R4J5
      Related
      ENSRNOP00000064282.2
      Conserved Domains (1) summary
      cd00882
      Location:211 → 283
      Ras_like_GTPase; Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases)
    Nucleotide Protein Strain
    Heading Accession and Version

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