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    Fam221a family with sequence similarity 221, member A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500118, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Fam221aprovided by RGD
    Official Full Name
    family with sequence similarity 221, member Aprovided by RGD
    Primary source
    RGD:1563175
    See related
    Ensembl:ENSRNOG00000009447 AllianceGenome:RGD:1563175
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Orthologous to human FAM221A (family with sequence similarity 221 member A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Testes (RPKM 48.9), Thymus (RPKM 17.6) and 6 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    4q24
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (79668130..79689768)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (78337296..78358918)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (79021840..79043806)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L17 pseudogene Neighboring gene translation machinery associated 7B Neighboring gene ribosomal protein S11 like 1 Neighboring gene serine threonine kinase 31

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC114484

    General protein information

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    Preferred Names
    protein FAM221A
    Names
    uncharacterized protein C7orf46 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025771.2 → NP_001020942.1  protein FAM221A

      See identical proteins and their annotated locations for NP_001020942.1

      Status: PROVISIONAL

      Source sequence(s)
      BC097434
      UniProtKB/TrEMBL
      A0A0G2JSY5, A0A8L2Q627
      Related
      ENSRNOP00000060562.1, ENSRNOT00000067125.3
      Conserved Domains (1) summary
      pfam14753
      Location:1 → 167
      DUF4475; Domain of unknown function (DUF4475)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      79668130..79689768
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017592793.3 → XP_017448282.1  protein FAM221A isoform X1

      UniProtKB/Swiss-Prot
      Q4V8D7
      UniProtKB/TrEMBL
      A0A8L2Q627
      Related
      ENSRNOP00000012677.7
      Conserved Domains (1) summary
      pfam14753
      Location:20 → 214
      DUF4475; Domain of unknown function (DUF4475)

    2. XM_006236468.5 → XP_006236530.1  protein FAM221A isoform X2

      See identical proteins and their annotated locations for XP_006236530.1

      UniProtKB/TrEMBL
      A0A8L2Q627, A6K0L0
      Related
      ENSRNOP00000084912.1
      Conserved Domains (1) summary
      pfam14753
      Location:20 → 214
      DUF4475; Domain of unknown function (DUF4475)

    3. XM_039108129.2 → XP_038964057.1  protein FAM221A isoform X3

      Conserved Domains (1) summary
      pfam14753
      Location:20 → 143
      FAM221; Protein FAM221A/B

    4. XM_039108130.2 → XP_038964058.1  protein FAM221A isoform X4

      Conserved Domains (1) summary
      pfam14753
      Location:20 → 143
      FAM221; Protein FAM221A/B
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4V8D7.2 GenPept UniProtKB/Swiss-Prot:Q4V8D7

    Gene LinkOut

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