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    Zfand5 zinc finger AN1-type containing 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293960, updated on 6-Jun-2024

    Summary

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    Official Symbol
    Zfand5provided by RGD
    Official Full Name
    zinc finger AN1-type containing 5provided by RGD
    Primary source
    RGD:1310776
    See related
    Ensembl:ENSRNOG00000018107 AllianceGenome:RGD:1310776
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Zfp216
    Summary
    Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to act upstream of or within several processes, including face development; fibroblast migration; and platelet-derived growth factor receptor signaling pathway. Predicted to be located in cytoplasm. Orthologous to human ZFAND5 (zinc finger AN1-type containing 5). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Muscle (RPKM 674.0), Adrenal (RPKM 412.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfand5 in Genome Data Viewer
    Location:
    1q51
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (228191064..228206947)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (218765735..218780391)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (238842506..238854030)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene uncharacterized LOC134483973 Neighboring gene uncharacterized LOC102551544 Neighboring gene uncharacterized LOC103691306 Neighboring gene uncharacterized LOC120100000 Neighboring gene small nucleolar RNA SNORA44 Neighboring gene guanine deaminase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. PDGF signaling specificity is mediated through multiple immediate early genes. Schmahl J, et al. Nat Genet, 2007 Jan. PMID 17143286
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in face development IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within face development ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in fibroblast migration IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within fibroblast migration ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in in utero embryonic development IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within in utero embryonic development ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in platelet-derived growth factor receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within platelet-derived growth factor receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in respiratory system process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within respiratory system process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in skeletal system morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within skeletal system morphogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in smooth muscle tissue development IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within smooth muscle tissue development ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in vasculature development IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within vasculature development ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    AN1-type zinc finger protein 5
    Names
    zinc finger protein 216
    zinc finger, AN1-type domain 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001401398.2 → NP_001388327.1  AN1-type zinc finger protein 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/Swiss-Prot
      B5DF11
      UniProtKB/TrEMBL
      A0A8I5YBX2
      Related
      ENSRNOP00000024583.4, ENSRNOT00000024583.6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      228191064..228206947
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039108958.2 → XP_038964886.1  AN1-type zinc finger protein 5 isoform X1

      UniProtKB/Swiss-Prot
      B5DF11
      UniProtKB/TrEMBL
      A0A8I5YBX2
      Related
      ENSRNOP00000076810.1
      Conserved Domains (2) summary
      smart00154
      Location:154 → 191
      ZnF_AN1; AN1-like Zinc finger
      pfam01754
      Location:12 → 34
      zf-A20; A20-like zinc finger

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001106356.1: Suppressed sequence

      Description
      NM_001106356.1: This RefSeq was removed because currently there is insufficient support for the transcript.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B5DF11.1 GenPept UniProtKB/Swiss-Prot:B5DF11

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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