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    Cct2 chaperonin containing Tcp1, subunit 2 (beta) [ Mus musculus (house mouse) ]

    Gene ID: 12461, updated on 23-Jun-2021

    Summary

    Official Symbol
    Cct2provided by MGI
    Official Full Name
    chaperonin containing Tcp1, subunit 2 (beta)provided by MGI
    Primary source
    MGI:MGI:107186
    See related
    Ensembl:ENSMUSG00000034024
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cctb
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 94.1), placenta adult (RPKM 81.3) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Cct2 in Genome Data Viewer
    Location:
    10; 10 D2
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (116886902..116899757, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (117050997..117063852, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (116488054..116500870, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene 10747 Neighboring gene leucine rich repeat containing 10 Neighboring gene fibroblast growth factor receptor substrate 2 Neighboring gene predicted gene, 40811 Neighboring gene predicted gene, 53635

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein folding chaperone ISO
    Inferred from Sequence Orthology
    more info
     
    enables ubiquitin protein ligase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables unfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of chaperonin-containing T-complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of chaperonin-containing T-complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of chaperonin-containing T-complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in myelin sheath HDA PubMed 
    part_of zona pellucida receptor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    T-complex protein 1 subunit beta
    Names
    CCT-beta
    TCP-1-beta
    chaperonin subunit 2 (beta)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001358767.1NP_001345696.1  T-complex protein 1 subunit beta

      Status: VALIDATED

      Source sequence(s)
      AK145406, BU755483, BY075050, CJ076140
      Conserved Domains (1) summary
      cd03336
      Location:11527
      TCP1_beta; TCP-1 (CTT or eukaryotic type II) chaperonin family, beta subunit. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings. In contrast to bacterial group I chaperonins (GroEL) ...
    2. NM_007636.3NP_031662.2  T-complex protein 1 subunit beta

      See identical proteins and their annotated locations for NP_031662.2

      Status: VALIDATED

      Source sequence(s)
      AK145406, AL589661, BU755483
      Consensus CDS
      CCDS36067.1
      UniProtKB/Swiss-Prot
      P80314
      UniProtKB/TrEMBL
      Q542X7
      Related
      ENSMUSP00000036288.8, ENSMUST00000047672.9
      Conserved Domains (1) summary
      cd03336
      Location:11527
      TCP1_beta; TCP-1 (CTT or eukaryotic type II) chaperonin family, beta subunit. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings. In contrast to bacterial group I chaperonins (GroEL) ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      116886902..116899757 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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