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    Eef1a2 eukaryotic translation elongation factor 1 alpha 2 [ Mus musculus (house mouse) ]

    Gene ID: 13628, updated on 8-Jul-2021

    Summary

    Official Symbol
    Eef1a2provided by MGI
    Official Full Name
    eukaryotic translation elongation factor 1 alpha 2provided by MGI
    Primary source
    MGI:MGI:1096317
    See related
    Ensembl:ENSMUSG00000016349
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    S; S1; STN; wst; Eef1; Eef1a; EEF1AL; wasted; EF-1-alpha-2
    Expression
    Biased expression in heart adult (RPKM 359.9), cerebellum adult (RPKM 338.2) and 6 other tissues See more
    Orthologs
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    Genomic context

    See Eef1a2 in Genome Data Viewer
    Location:
    2 H4; 2 103.6 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (180783551..180798808, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (181141758..181157015, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (180882397..180891720, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene cholinergic receptor, nicotinic, alpha polypeptide 4 Neighboring gene potassium voltage-gated channel, subfamily Q, member 2 Neighboring gene predicted gene, 24892 Neighboring gene pancreatic progenitor cell differentiation and proliferation factor

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Spontaneous (1) 
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables translation elongation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables translation elongation factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of apoptotic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of lipid kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in translational elongation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within translational elongation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of eukaryotic translation elongation factor 1 complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in myelin sheath HDA PubMed 
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    elongation factor 1-alpha 2
    Names
    eukaryotic elongation factor 1 A-2
    statin-S1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007906.3NP_031932.1  elongation factor 1-alpha 2

      See identical proteins and their annotated locations for NP_031932.1

      Status: VALIDATED

      Source sequence(s)
      AL450341, BC018235, BC060606, BE656626
      Consensus CDS
      CCDS17201.1
      UniProtKB/Swiss-Prot
      P62631
      Related
      ENSMUSP00000054556.8, ENSMUST00000055990.8
      Conserved Domains (1) summary
      PTZ00141
      Location:1460
      PTZ00141; elongation factor 1- alpha; Provisional

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      180783551..180798808 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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