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    Icam5 intercellular adhesion molecule 5, telencephalin [ Mus musculus (house mouse) ]

    Gene ID: 15898, updated on 23-Jun-2021

    Summary

    Official Symbol
    Icam5provided by MGI
    Official Full Name
    intercellular adhesion molecule 5, telencephalinprovided by MGI
    Primary source
    MGI:MGI:109430
    See related
    Ensembl:ENSMUSG00000032174
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    T; Tl; Ica; TLN; CD50; Tlcn; Icam3; ICAM-3
    Expression
    Biased expression in frontal lobe adult (RPKM 62.6), cortex adult (RPKM 49.2) and 1 other tissue See more
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    Genomic context

    See Icam5 in Genome Data Viewer
    Location:
    9 A3; 9 7.7 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (20943158..20950332)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (21032038..21039036)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (20836482..20843480)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene intercellular adhesion molecule 1 Neighboring gene intercellular adhesion molecule 4, Landsteiner-Wiener blood group Neighboring gene microRNA 1900 Neighboring gene zinc finger, GATA-like protein 1 Neighboring gene predicted gene, 38431 Neighboring gene ferredoxin 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1)  1 citation
    • Endonuclease-mediated (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC130520

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables integrin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within phagocytosis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    intercellular adhesion molecule 5
    Names
    ICAM-5
    intercellular adhesion molecule 3
    telencephalin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008319.2NP_032345.2  intercellular adhesion molecule 5 precursor

      See identical proteins and their annotated locations for NP_032345.2

      Status: VALIDATED

      Source sequence(s)
      AC159314, AK135040, BB299138, BC113140, BY255874
      Consensus CDS
      CCDS22891.1
      UniProtKB/Swiss-Prot
      Q60625
      Related
      ENSMUSP00000019616.5, ENSMUST00000019616.6
      Conserved Domains (6) summary
      cd05755
      Location:120219
      Ig2_ICAM-1_like; Second immunoglobulin (Ig)-like domain of intercellular cell adhesion molecule-1 (ICAM-1, CD54) and similar proteins
      smart00408
      Location:759819
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:756829
      IG_like; Immunoglobulin like
      pfam03921
      Location:32103
      ICAM_N; Intercellular adhesion molecule (ICAM), N-terminal domain
      pfam07679
      Location:572659
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:687742
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      20943158..20950332
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036154614.1XP_036010507.1  intercellular adhesion molecule 5 isoform X1

      Conserved Domains (3) summary
      smart00409
      Location:577650
      IG; Immunoglobulin
      cd00096
      Location:17
      Ig; Ig strand E [structural motif]
      cl11960
      Location:140
      Ig; Immunoglobulin domain
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