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    Dpy30 dpy-30, histone methyltransferase complex regulatory subunit [ Mus musculus (house mouse) ]

    Gene ID: 66310, updated on 23-Jun-2021

    Summary

    Official Symbol
    Dpy30provided by MGI
    Official Full Name
    dpy-30, histone methyltransferase complex regulatory subunitprovided by MGI
    Primary source
    MGI:MGI:1913560
    See related
    Ensembl:ENSMUSG00000024067
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C87842; 2810410M20Rik
    Expression
    Ubiquitous expression in liver E14 (RPKM 36.7), testis adult (RPKM 34.1) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Dpy30 in Genome Data Viewer
    Location:
    17; 17 E2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (74606469..74630939, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (74299474..74323944, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (74698814..74723284, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene mediator of cell motility 1 Neighboring gene F-box protein 34 pseudogene Neighboring gene predicted gene, 52299 Neighboring gene predicted gene, 31328 Neighboring gene predicted gene 9349

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chromatin silencing at telomere IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in endosomal transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in histone H3-K4 methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in histone H3-K4 methylation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of MLL3/4 complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of Set1C/COMPASS complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of Set1C/COMPASS complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of histone methyltransferase complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in trans-Golgi network ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein dpy-30 homolog
    Names
    dosage compensation-related protein DPY30
    dpy-30 homolog
    dpy-30-like protein
    dpy-30L

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001146222.1NP_001139694.1  protein dpy-30 homolog

      See identical proteins and their annotated locations for NP_001139694.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1-4 encode the same protein.
      Source sequence(s)
      AK013073, BX518196
      Consensus CDS
      CCDS28970.1
      UniProtKB/Swiss-Prot
      Q99LT0
      Related
      ENSMUSP00000108190.4, ENSMUST00000112571.5
      Conserved Domains (1) summary
      pfam05186
      Location:5293
      Dpy-30; Dpy-30 motif
    2. NM_001146223.1NP_001139695.1  protein dpy-30 homolog

      See identical proteins and their annotated locations for NP_001139695.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1-4 encode the same protein.
      Source sequence(s)
      AK013073, AK077902, AV460563
      Consensus CDS
      CCDS28970.1
      UniProtKB/Swiss-Prot
      Q99LT0
      Related
      ENSMUSP00000156795.2, ENSMUST00000233581.2
      Conserved Domains (1) summary
      pfam05186
      Location:5293
      Dpy-30; Dpy-30 motif
    3. NM_001146224.1NP_001139696.1  protein dpy-30 homolog

      See identical proteins and their annotated locations for NP_001139696.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1. Variants 1-4 encode the same protein.
      Source sequence(s)
      AK003688, AK013073, BY123406
      Consensus CDS
      CCDS28970.1
      UniProtKB/Swiss-Prot
      Q99LT0
      Related
      ENSMUSP00000156830.2, ENSMUST00000232687.2
      Conserved Domains (1) summary
      pfam05186
      Location:5293
      Dpy-30; Dpy-30 motif
    4. NM_024428.4NP_077746.3  protein dpy-30 homolog

      See identical proteins and their annotated locations for NP_077746.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1-4 encode the same protein.
      Source sequence(s)
      AK013073, BU961422
      Consensus CDS
      CCDS28970.1
      UniProtKB/Swiss-Prot
      Q99LT0
      Related
      ENSMUSP00000126702.2, ENSMUST00000164832.9
      Conserved Domains (1) summary
      pfam05186
      Location:5293
      Dpy-30; Dpy-30 motif

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      74606469..74630939 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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