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    Chchd5 coiled-coil-helix-coiled-coil-helix domain containing 5 [ Mus musculus (house mouse) ]

    Gene ID: 66170, updated on 2-Apr-2024

    Summary

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    Official Symbol
    Chchd5provided by MGI
    Official Full Name
    coiled-coil-helix-coiled-coil-helix domain containing 5provided by MGI
    Primary source
    MGI:MGI:1913420
    See related
    Ensembl:ENSMUSG00000037938 AllianceGenome:MGI:1913420
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110027L01Rik
    Summary
    Predicted to be located in mitochondrion. Is expressed in orbito-sphenoid and turbinate bone primordium. Orthologous to human CHCHD5 (coiled-coil-helix-coiled-coil-helix domain containing 5). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 37.7), liver adult (RPKM 19.0) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    2 F1; 2 62.72 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (128971620..128976032)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (129129700..129134112)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene tubulin tyrosine ligase Neighboring gene predicted gene, 46764 Neighboring gene polymerase (RNA) I polypeptide B Neighboring gene SET domain containing 3 pseudogene Neighboring gene STARR-seq mESC enhancer starr_05661 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:129005758-129006030 Neighboring gene expressed sequence AI847159

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular respiration IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial intermembrane space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil-helix-coiled-coil-helix domain-containing protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025395.3 → NP_079671.1  coiled-coil-helix-coiled-coil-helix domain-containing protein 5

      See identical proteins and their annotated locations for NP_079671.1

      Status: VALIDATED

      Source sequence(s)
      AK013018, BB792161, BY335381, W41426
      Consensus CDS
      CCDS16721.1
      UniProtKB/Swiss-Prot
      Q9CQP3
      UniProtKB/TrEMBL
      Q52KC5
      Related
      ENSMUSP00000044253.5, ENSMUST00000035481.5
      Conserved Domains (2) summary
      pfam06747
      Location:58 → 92
      CHCH; CHCH domain
      pfam16860
      Location:8 → 49
      CX9C; CHCH-CHCH-like Cx9C, IMS import disulfide relay-system,

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      128971620..128976032
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CQP3.1 GenPept UniProtKB/Swiss-Prot:Q9CQP3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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