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    Laptm4b lysosomal-associated protein transmembrane 4B [ Mus musculus (house mouse) ]

    Gene ID: 114128, updated on 23-Jun-2021

    Summary

    Official Symbol
    Laptm4bprovided by MGI
    Official Full Name
    lysosomal-associated protein transmembrane 4Bprovided by MGI
    Primary source
    MGI:MGI:1890494
    See related
    Ensembl:ENSMUSG00000022257
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    LAPTM4beta; C330023P13Rik
    Expression
    Ubiquitous expression in adrenal adult (RPKM 150.7), ovary adult (RPKM 83.2) and 24 other tissues See more
    Orthologs
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    Genomic context

    See Laptm4b in Genome Data Viewer
    Location:
    15; 15 B3.1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (34238172..34284441)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (34238026..34284295)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (34167781..34214050)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41291 Neighboring gene metadherin Neighboring gene predicted gene, 38594 Neighboring gene eukaryotic translation initiation factor 4A2 pseudogene Neighboring gene matrilin 2 Neighboring gene RIKEN cDNA 9430069I07 gene Neighboring gene predicted gene, 24523 Neighboring gene ribosomal protein L30

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ceramide binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables phosphatidylinositol bisphosphate binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ubiquitin protein ligase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cell projection ISO
    Inferred from Sequence Orthology
    more info
     
    located_in early endosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in late endosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in lysosomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in lysosomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in multivesicular body membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in multivesicular body, internal vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    lysosomal-associated transmembrane protein 4B
    Names
    lysosomal-associated transmembrane protein 4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_033521.3NP_277056.1  lysosomal-associated transmembrane protein 4B

      See identical proteins and their annotated locations for NP_277056.1

      Status: PROVISIONAL

      Source sequence(s)
      AC133101
      Consensus CDS
      CCDS27416.1
      UniProtKB/Swiss-Prot
      Q91XQ6
      UniProtKB/TrEMBL
      B2CZK6
      Related
      ENSMUSP00000022867.4, ENSMUST00000022867.5
      Conserved Domains (1) summary
      cl04276
      Location:9227
      Mtp; Golgi 4-transmembrane spanning transporter

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      34238172..34284441
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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