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    Akap13 A kinase (PRKA) anchor protein 13 [ Mus musculus (house mouse) ]

    Gene ID: 75547, updated on 23-Jun-2021

    Summary

    Official Symbol
    Akap13provided by MGI
    Official Full Name
    A kinase (PRKA) anchor protein 13provided by MGI
    Primary source
    MGI:MGI:2676556
    See related
    Ensembl:ENSMUSG00000066406
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BRX; LBC; PRO; AKAP; Ht31; PROT; AKAP-13; AKAP-Lbc; PROTO-LB; PROTO-LBC; 1700026G02Rik; 5730522G15Rik; 5830460E08Rik
    Expression
    Ubiquitous expression in spleen adult (RPKM 15.7), lung adult (RPKM 14.2) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Akap13 in Genome Data Viewer
    Location:
    7; 7 D1
    Exon count:
    42
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (75105271..75404357)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (75455526..75754609)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (82600420..82899495)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein S28 pseudogene Neighboring gene predicted gene, 46017 Neighboring gene CRISPRi-validated cis-regulatory element for Akap13 Neighboring gene expressed sequence AU020206 Neighboring gene predicted gene, 51489

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (3) 
    • Targeted (1)  1 citation
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables MAP-kinase scaffold activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables MAP-kinase scaffold activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables cAMP-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables guanyl-nucleotide exchange factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables guanyl-nucleotide exchange factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular adaptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein kinase A binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables small GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in adrenergic receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in adrenergic receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in bone development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cardiac muscle cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cell growth involved in cardiac muscle cell development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in heart development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in nuclear export ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of MAP kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of Rho protein signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of Rho protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within regulation of glucocorticoid mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of sarcomere organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    colocalizes_with actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with actin cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with actin filament IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell cortex ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with cortical actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    A-kinase anchor protein 13
    Names
    type II cAMP-dependent protein kinase anchoring protein Ht31

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029332.1NP_083608.1  A-kinase anchor protein 13

      Status: VALIDATED

      Source sequence(s)
      AC113019, AC158749
      Consensus CDS
      CCDS52276.1
      UniProtKB/Swiss-Prot
      E9Q394
      Related
      ENSMUSP00000129784.2, ENSMUST00000166315.7
      Conserved Domains (6) summary
      cd00160
      Location:19582152
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd13392
      Location:21952297
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      pfam00169
      Location:21952295
      PH; PH domain
      pfam02050
      Location:25352645
      FliJ; Flagellar FliJ protein
      cl00040
      Location:17551801
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cl02529
      Location:165219
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      75105271..75404357
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036153520.1XP_036009413.1  A-kinase anchor protein 13 isoform X1

      Conserved Domains (5) summary
      cd00160
      Location:19992193
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:25192674
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd13392
      Location:22362338
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cd20878
      Location:17921848
      C1_AKAP13; protein kinase C conserved region 1 (C1 domain) found in A-kinase anchor protein 13 (AKAP-13) and similar proteins
      NF033909
      Location:11501298
      opacity_OapA; opacity-associated protein OapA
    2. XM_036153522.1XP_036009415.1  A-kinase anchor protein 13 isoform X3

      Conserved Domains (6) summary
      PRK12704
      Location:26162686
      PRK12704; phosphodiesterase; Provisional
      cd00160
      Location:19992193
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:25322673
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd13392
      Location:22362338
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cd20878
      Location:17921848
      C1_AKAP13; protein kinase C conserved region 1 (C1 domain) found in A-kinase anchor protein 13 (AKAP-13) and similar proteins
      NF033909
      Location:11501298
      opacity_OapA; opacity-associated protein OapA
    3. XM_036153521.1XP_036009414.1  A-kinase anchor protein 13 isoform X2

      Conserved Domains (5) summary
      cd00160
      Location:19982192
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:25182673
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd13392
      Location:22352337
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cd20878
      Location:17921848
      C1_AKAP13; protein kinase C conserved region 1 (C1 domain) found in A-kinase anchor protein 13 (AKAP-13) and similar proteins
      NF033909
      Location:11501298
      opacity_OapA; opacity-associated protein OapA
    4. XM_036153523.1XP_036009416.1  A-kinase anchor protein 13 isoform X4

      Conserved Domains (5) summary
      cd00160
      Location:19972191
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:25172672
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd13392
      Location:22342336
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cd20878
      Location:17921848
      C1_AKAP13; protein kinase C conserved region 1 (C1 domain) found in A-kinase anchor protein 13 (AKAP-13) and similar proteins
      NF033909
      Location:11501298
      opacity_OapA; opacity-associated protein OapA
    5. XM_036153525.1XP_036009418.1  A-kinase anchor protein 13 isoform X6

      Conserved Domains (6) summary
      PRK12704
      Location:25952665
      PRK12704; phosphodiesterase; Provisional
      cd00160
      Location:19772171
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:24972652
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd13392
      Location:22142316
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cd20878
      Location:17701826
      C1_AKAP13; protein kinase C conserved region 1 (C1 domain) found in A-kinase anchor protein 13 (AKAP-13) and similar proteins
      NF033909
      Location:11501298
      opacity_OapA; opacity-associated protein OapA
    6. XM_036153526.1XP_036009419.1  A-kinase anchor protein 13 isoform X8

      Conserved Domains (6) summary
      PRK12704
      Location:25932663
      PRK12704; phosphodiesterase; Provisional
      cd00160
      Location:19752169
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:24952650
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd13392
      Location:22122314
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cd20878
      Location:17701826
      C1_AKAP13; protein kinase C conserved region 1 (C1 domain) found in A-kinase anchor protein 13 (AKAP-13) and similar proteins
      NF033909
      Location:11501298
      opacity_OapA; opacity-associated protein OapA
    7. XM_036153524.1XP_036009417.1  A-kinase anchor protein 13 isoform X5

      Conserved Domains (5) summary
      cd00160
      Location:19812175
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:25012656
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd13392
      Location:22182320
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cd20878
      Location:17741830
      C1_AKAP13; protein kinase C conserved region 1 (C1 domain) found in A-kinase anchor protein 13 (AKAP-13) and similar proteins
      NF033909
      Location:11501298
      opacity_OapA; opacity-associated protein OapA
    8. XM_036153527.1XP_036009420.1  A-kinase anchor protein 13 isoform X9

      Conserved Domains (6) summary
      PRK12704
      Location:25772647
      PRK12704; phosphodiesterase; Provisional
      cd00160
      Location:19592153
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:24792634
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd13392
      Location:21962298
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cd20878
      Location:17521808
      C1_AKAP13; protein kinase C conserved region 1 (C1 domain) found in A-kinase anchor protein 13 (AKAP-13) and similar proteins
      NF033909
      Location:11501298
      opacity_OapA; opacity-associated protein OapA
    9. XM_036153528.1XP_036009421.1  A-kinase anchor protein 13 isoform X11

      Conserved Domains (6) summary
      PRK12704
      Location:25752645
      PRK12704; phosphodiesterase; Provisional
      cd00160
      Location:19572151
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:24772632
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd13392
      Location:21942296
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cd20878
      Location:17521808
      C1_AKAP13; protein kinase C conserved region 1 (C1 domain) found in A-kinase anchor protein 13 (AKAP-13) and similar proteins
      NF033909
      Location:11501298
      opacity_OapA; opacity-associated protein OapA
    10. XM_006541256.4XP_006541319.1  A-kinase anchor protein 13 isoform X7

      UniProtKB/TrEMBL
      A0A140LJJ5
      Related
      ENSMUSP00000147237.2, ENSMUST00000207750.2
      Conserved Domains (5) summary
      cd00160
      Location:19762170
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:25532676
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      TIGR03835
      Location:450835
      termin_org_DnaJ; terminal organelle assembly protein TopJ
      cd13392
      Location:22132315
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cl00040
      Location:17731819
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    11. XM_006541254.5XP_006541317.1  A-kinase anchor protein 13 isoform X12

      Conserved Domains (5) summary
      cd00160
      Location:19542148
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:25312654
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      TIGR03835
      Location:450835
      termin_org_DnaJ; terminal organelle assembly protein TopJ
      cd13392
      Location:21912293
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cl00040
      Location:17511797
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    12. XM_006541253.5XP_006541316.1  A-kinase anchor protein 13 isoform X10

      Conserved Domains (5) summary
      cd00160
      Location:19582152
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:25352658
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      TIGR03835
      Location:450835
      termin_org_DnaJ; terminal organelle assembly protein TopJ
      cd13392
      Location:21952297
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cl00040
      Location:17551801
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    13. XM_006541255.5XP_006541318.1  A-kinase anchor protein 13 isoform X13

      UniProtKB/Swiss-Prot
      E9Q394
      Conserved Domains (5) summary
      cd00160
      Location:19362130
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:25132636
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      TIGR03835
      Location:450835
      termin_org_DnaJ; terminal organelle assembly protein TopJ
      cd13392
      Location:21732275
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cl00040
      Location:17331779
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    14. XM_030243062.2XP_030098922.1  A-kinase anchor protein 13 isoform X14

      Conserved Domains (5) summary
      cd00160
      Location:19352129
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:25122635
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      TIGR03835
      Location:450835
      termin_org_DnaJ; terminal organelle assembly protein TopJ
      cd13392
      Location:21722274
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cl00040
      Location:17331779
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    15. XM_036153529.1XP_036009422.1  A-kinase anchor protein 13 isoform X15

      Conserved Domains (6) summary
      PRK12704
      Location:24092479
      PRK12704; phosphodiesterase; Provisional
      cd00160
      Location:17911985
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:23112466
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd13392
      Location:20282130
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cd20878
      Location:15841640
      C1_AKAP13; protein kinase C conserved region 1 (C1 domain) found in A-kinase anchor protein 13 (AKAP-13) and similar proteins
      NF033909
      Location:9421090
      opacity_OapA; opacity-associated protein OapA
    16. XM_036153530.1XP_036009423.1  A-kinase anchor protein 13 isoform X16

      Conserved Domains (5) summary
      PRK12704
      Location:13101380
      PRK12704; phosphodiesterase; Provisional
      cd00160
      Location:692886
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:12121367
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd13392
      Location:9291031
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cd20878
      Location:485541
      C1_AKAP13; protein kinase C conserved region 1 (C1 domain) found in A-kinase anchor protein 13 (AKAP-13) and similar proteins
    17. XM_006541258.5XP_006541321.1  A-kinase anchor protein 13 isoform X17

      Conserved Domains (4) summary
      cd00160
      Location:669863
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:12461369
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd13392
      Location:9061008
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cl00040
      Location:466512
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    18. XM_036153531.1XP_036009424.1  A-kinase anchor protein 13 isoform X18

      Conserved Domains (5) summary
      PRK12704
      Location:12851355
      PRK12704; phosphodiesterase; Provisional
      cd00160
      Location:667861
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:11871342
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd13392
      Location:9041006
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cd20878
      Location:462518
      C1_AKAP13; protein kinase C conserved region 1 (C1 domain) found in A-kinase anchor protein 13 (AKAP-13) and similar proteins
    19. XM_030243065.2XP_030098925.1  A-kinase anchor protein 13 isoform X21

      Conserved Domains (4) summary
      cd00160
      Location:629823
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:12061329
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd13392
      Location:866968
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cl00040
      Location:426472
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    20. XM_006541259.5XP_006541322.1  A-kinase anchor protein 13 isoform X19

      Conserved Domains (4) summary
      cd00160
      Location:654848
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:12311354
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd13392
      Location:891993
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cl00040
      Location:451497
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    21. XM_036153532.1XP_036009425.1  A-kinase anchor protein 13 isoform X20

      Conserved Domains (5) summary
      PRK12704
      Location:12541324
      PRK12704; phosphodiesterase; Provisional
      cd00160
      Location:636830
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:11561311
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd13392
      Location:873975
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cd20878
      Location:429485
      C1_AKAP13; protein kinase C conserved region 1 (C1 domain) found in A-kinase anchor protein 13 (AKAP-13) and similar proteins
    22. XM_006541260.5XP_006541323.1  A-kinase anchor protein 13 isoform X22

      Conserved Domains (4) summary
      cd00160
      Location:614808
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:11911314
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd13392
      Location:851953
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cl00040
      Location:411457
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    23. XM_036153533.1XP_036009426.1  A-kinase anchor protein 13 isoform X23

      Conserved Domains (5) summary
      PRK12704
      Location:12311301
      PRK12704; phosphodiesterase; Provisional
      cd00160
      Location:613807
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      TIGR02168
      Location:11331288
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd13392
      Location:850952
      PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
      cd20878
      Location:407463
      C1_AKAP13; protein kinase C conserved region 1 (C1 domain) found in A-kinase anchor protein 13 (AKAP-13) and similar proteins
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