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    Tspan7 tetraspanin 7 [ Mus musculus (house mouse) ]

    Gene ID: 21912, updated on 23-Jun-2021

    Summary

    Official Symbol
    Tspan7provided by MGI
    Official Full Name
    tetraspanin 7provided by MGI
    Primary source
    MGI:MGI:1298407
    See related
    Ensembl:ENSMUSG00000058254
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    T; A1; A15; PE3; Mxs1; PE31; Cd231; TALLA; Tm4sf; R74651; Tm4sf2; AI323365; 1200014P11Rik
    Expression
    Biased expression in cortex adult (RPKM 421.3), frontal lobe adult (RPKM 387.8) and 14 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Tspan7 in Genome Data Viewer
    Location:
    X; X A1.1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (10351355..10462843)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (10485116..10596604)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (10062242..10173730)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene ferritin light chain pseudogene Neighboring gene predicted gene, 54081 Neighboring gene ubiquitin-conjugating enzyme E2I pseudogene Neighboring gene lactate dehydrogenase A pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1)  1 citation
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    tetraspanin-7
    Names
    TALLA homolog
    cell surface glycoprotein A15
    transmembrane 4 superfamily member 2
    tspan-7

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019634.2NP_062608.2  tetraspanin-7

      See identical proteins and their annotated locations for NP_062608.2

      Status: VALIDATED

      Source sequence(s)
      AI854904, AK004776, BY238972
      Consensus CDS
      CCDS30016.1
      UniProtKB/Swiss-Prot
      Q62283
      Related
      ENSMUSP00000075692.7, ENSMUST00000076354.13
      Conserved Domains (2) summary
      cd03161
      Location:110213
      TM4SF2_6_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), TM4SF2_6_like subfamily. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
      pfam00335
      Location:15237
      Tetraspannin; Tetraspanin family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      10351355..10462843
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036161904.1XP_036017797.1  tetraspanin-7 isoform X1

      Conserved Domains (1) summary
      cd03161
      Location:24127
      TM4SF2_6_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), TM4SF2_6_like subfamily. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
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