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    Ppp1r14b protein phosphatase 1, regulatory inhibitor subunit 14B [ Mus musculus (house mouse) ]

    Gene ID: 18938, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ppp1r14bprovided by MGI
    Official Full Name
    protein phosphatase 1, regulatory inhibitor subunit 14Bprovided by MGI
    Primary source
    MGI:MGI:107682
    See related
    Ensembl:ENSMUSG00000056612
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    P; PHI; PLC; Png; AOM1; PHI-1; AOM172; PLCB3N
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 114.0), CNS E14 (RPKM 112.7) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Ppp1r14b in Genome Data Viewer
    Location:
    19; 19 A
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (6952416..6954692)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (6975048..6977324)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (7049538..7051814)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene BCL2-associated agonist of cell death Neighboring gene ATG2 autophagy related 2 homolog A pseudogene Neighboring gene phospholipase C, beta 3 Neighboring gene predicted gene, 52400 Neighboring gene predicted gene, 51400 Neighboring gene FK506 binding protein 2 Neighboring gene predicted gene, 54053 Neighboring gene vascular endothelial growth factor B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables phosphatase inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein phosphatase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein phosphatase regulator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein serine/threonine phosphatase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein phosphatase 1 regulatory subunit 14B
    Names
    phosphatase holoenzyme inhibitor 1
    phospholipase C-beta-3 neighbouring gene protein
    phospholipase c neighboring

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008889.2NP_032915.2  protein phosphatase 1 regulatory subunit 14B

      See identical proteins and their annotated locations for NP_032915.2

      Status: VALIDATED

      Source sequence(s)
      BC082545, CF739461
      Consensus CDS
      CCDS29514.1
      UniProtKB/Swiss-Prot
      Q62084
      Related
      ENSMUSP00000064129.7, ENSMUST00000070850.8
      Conserved Domains (1) summary
      pfam05361
      Location:51147
      PP1_inhibitor; PKC-activated protein phosphatase-1 inhibitor

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      6952416..6954692
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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