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    Zfp991 zinc finger protein 991 [ Mus musculus (house mouse) ]

    Gene ID: 666532, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Zfp991provided by MGI
    Official Full Name
    zinc finger protein 991provided by MGI
    Primary source
    MGI:MGI:3701604
    See related
    Ensembl:ENSMUSG00000067916 AllianceGenome:MGI:3701604
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm13139
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in genitourinary system. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in bladder adult (RPKM 5.2), testis adult (RPKM 4.8) and 19 other tissues See more
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    Genomic context

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    Location:
    4 E1; 4 78.44 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (147198335..147266219)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (147132093..147180579)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene 13160 Neighboring gene predicted gene 13142 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145951820-145952121 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146498255-146498556 Neighboring gene vomeronasal 2, receptor, pseudogene 18 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146506000-146506300 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146516417-146516717 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146546713-146547013 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146548117-146548418 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146549342-146549643 Neighboring gene carnitine deficiency-associated gene expressed in ventricle 3 pseudogene Neighboring gene 60S acidic ribosomal protein P1 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    2. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    3. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
    4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC19361

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC666532
    Names
    novel KRAB box domain containing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083918.1 → NP_001077387.1  uncharacterized protein LOC666532

      See identical proteins and their annotated locations for NP_001077387.1

      Status: PREDICTED

      Source sequence(s)
      BC024323
      Consensus CDS
      CCDS38961.1
      UniProtKB/TrEMBL
      Q8R1N3
      Related
      ENSMUSP00000081167.4, ENSMUST00000084149.10
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      147198335..147266219
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036164340.1 → XP_036020233.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    2. XM_036164329.1 → XP_036020222.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    3. XM_036164331.1 → XP_036020224.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    4. XM_036164333.1 → XP_036020226.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    5. XM_036164337.1 → XP_036020230.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    6. XM_036164328.1 → XP_036020221.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    7. XM_036164335.1 → XP_036020228.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    8. XM_036164330.1 → XP_036020223.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    9. XM_036164338.1 → XP_036020231.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    10. XM_036164334.1 → XP_036020227.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    11. XM_036164342.1 → XP_036020235.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    12. XM_036164323.1 → XP_036020216.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    13. XM_036164317.1 → XP_036020210.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    14. XM_036164322.1 → XP_036020215.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    15. XM_036164318.1 → XP_036020211.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    16. XM_036164324.1 → XP_036020217.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    17. XM_036164319.1 → XP_036020212.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    18. XM_036164325.1 → XP_036020218.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    19. XM_036164320.1 → XP_036020213.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    20. XM_036164326.1 → XP_036020219.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    21. XM_036164321.1 → XP_036020214.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    22. XM_036164327.1 → XP_036020220.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    23. XM_036164339.1 → XP_036020232.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    24. XM_036164332.1 → XP_036020225.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    25. XM_036164336.1 → XP_036020229.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    26. XM_036164343.1 → XP_036020236.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    27. XM_036164341.1 → XP_036020234.1  uncharacterized protein LOC666532 isoform X1

      UniProtKB/TrEMBL
      Q8R1N3
      Conserved Domains (3) summary
      COG5048
      Location:266 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:270 → 290
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box
    Nucleotide Protein Strain
    Heading Accession and Version

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