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Mef2c myocyte enhancer factor 2C [ Mus musculus (house mouse) ]

Gene ID: 17260, updated on 11-Apr-2024

Summary

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Official Symbol: Mef2cprovided by MGI
Official Full Name: myocyte enhancer factor 2Cprovided by MGI
Primary source: MGI:MGI:99458
See related: Ensembl:ENSMUSG00000005583 AllianceGenome:MGI:99458
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Mef2; 5430401D19Rik; 9930028G15Rik
Summary: Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; HMG box domain binding activity; and histone deacetylase binding activity. Involved in several processes, including animal organ development; modulation of chemical synaptic transmission; and positive regulation of cell differentiation. Acts upstream of or within several processes, including animal organ development; cardiac muscle hypertrophy in response to stress; and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; heart; limb; and urinary system. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 20. Orthologous to human MEF2C (myocyte enhancer factor 2C). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in cortex adult (RPKM 49.3), frontal lobe adult (RPKM 37.4) and 11 other tissues See more
Orthologs: human all
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Genomic context

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See Mef2c in Genome Data Viewer

Location:: 13 C3; 13 43.68 cM

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	13	NC_000079.7 (83652136..83815197)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	13	NC_000079.6 (83504017..83667079)

Chromosome 13 - NC_000079.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

METTL3 promotes microglial inflammation via MEF2C in spinal cord injury.
Title: METTL3 promotes microglial inflammation via MEF2C in spinal cord injury.
The Mef2c Gene Dose-Dependently Controls Hippocampal Neurogenesis and the Expression of Autism-Like Behaviors.
Title: The Mef2c Gene Dose-Dependently Controls Hippocampal Neurogenesis and the Expression of Autism-Like Behaviors.
Mef2c regulates bone mass through Sost-dependent and -independent mechanisms.
Title: Mef2c regulates bone mass through Sost-dependent and -independent mechanisms.
LncRNA SNHG14 activates autophagy via regulating miR-493-5p/Mef2c axis to alleviate osteoporosis progression.
Title: LncRNA SNHG14 activates autophagy via regulating miR-493-5p/Mef2c axis to alleviate osteoporosis progression.
Genes positively regulated by Mef2c in cortical neurons are enriched for common genetic variation associated with IQ and educational attainment.
Title: Genes positively regulated by Mef2c in cortical neurons are enriched for common genetic variation associated with IQ and educational attainment.
Conditional Loss of MEF2C Expression in Osteoclasts Leads to a Sex-Specific Osteopenic Phenotype.
Title: Conditional Loss of MEF2C Expression in Osteoclasts Leads to a Sex-Specific Osteopenic Phenotype.
Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience.
Title: Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience.
Overexpressing lnc240 Rescues Learning and Memory Dysfunction in Hepatic Encephalopathy Through miR-1264-5p/MEF2C Axis.
Title: Overexpressing lnc240 Rescues Learning and Memory Dysfunction in Hepatic Encephalopathy Through miR-1264-5p/MEF2C Axis.
Microglial priming induced by loss of Mef2C contributes to postoperative cognitive dysfunction in aged mice.
Title: Microglial priming induced by loss of Mef2C contributes to postoperative cognitive dysfunction in aged mice.
Actin-related protein 5 suppresses the cooperative activation of cardiac gene transcription by myocardin and MEF2.
Title: Actin-related protein 5 suppresses the cooperative activation of cardiac gene transcription by myocardin and MEF2.

Submit: New GeneRIF Correction See all GeneRIFs (169)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (9) 1 citation
Chemically induced (ENU) (1)
Endonuclease-mediated (4) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

NoName (e-PCR)
- UniSTS:548381

NoName (e-PCR)
- UniSTS:224809

Mef2c (e-PCR), detects polymorphism
- UniSTS:498478

STS-Z40067 (e-PCR)
- UniSTS:33841

BB372133 (e-PCR)
- UniSTS:208961

D13Mit233 (e-PCR), detects polymorphism
- UniSTS:127048

RH133929 (e-PCR)
- UniSTS:217212

Mef2c (e-PCR), detects polymorphism
- UniSTS:265602

Mef2c (e-PCR), detects polymorphism
- UniSTS:265603

Mef2c (e-PCR), detects polymorphism
- UniSTS:265604

SGC30495 (e-PCR)
- UniSTS:62611

Mef2c (e-PCR), detects polymorphism
- UniSTS:496803

PMC165676P1 (e-PCR)
- UniSTS:271544

Mef2c (e-PCR), detects polymorphism
- UniSTS:507064

Mef2c (e-PCR), detects polymorphism
- UniSTS:498391

G10647 (e-PCR)
- UniSTS:17885

Mef2c (e-PCR), detects polymorphism
- UniSTS:143852

Mef2c (e-PCR), detects polymorphism
- UniSTS:143853

Mef2c (e-PCR), detects polymorphism
- UniSTS:143854

AV011172 (e-PCR)
- UniSTS:165883

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables DNA binding	ISO Inferred from Sequence Orthology more info
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IMP Inferred from Mutant Phenotype more info	PubMed
enables DNA-binding transcription activator activity, RNA polymerase II-specific	ISO Inferred from Sequence Orthology more info
enables DNA-binding transcription factor activity	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor activity	ISO Inferred from Sequence Orthology more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor activity, RNA polymerase II-specific	ISO Inferred from Sequence Orthology more info
enables DNA-binding transcription factor binding	ISO Inferred from Sequence Orthology more info
enables HMG box domain binding	IPI Inferred from Physical Interaction more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO Inferred from Sequence Orthology more info
enables RNA polymerase II-specific DNA-binding transcription factor binding	ISO Inferred from Sequence Orthology more info
enables chromatin binding	IDA Inferred from Direct Assay more info	PubMed
enables cis-regulatory region sequence-specific DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables histone deacetylase binding	IBA Inferred from Biological aspect of Ancestor more info
enables histone deacetylase binding	IPI Inferred from Physical Interaction more info	PubMed
enables minor groove of adenine-thymine-rich DNA binding	ISO Inferred from Sequence Orthology more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info
enables protein heterodimerization activity	ISO Inferred from Sequence Orthology more info
enables sequence-specific DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables sequence-specific double-stranded DNA binding	ISO Inferred from Sequence Orthology more info
enables transcription cis-regulatory region binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_negative_effect AMPA selective glutamate receptor signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in B cell homeostasis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in B cell proliferation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in B cell receptor signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in MAPK cascade	IDA Inferred from Direct Assay more info	PubMed
involved_in MAPK cascade	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in MAPK cascade	ISO Inferred from Sequence Orthology more info
acts_upstream_of_negative_effect NMDA selective glutamate receptor signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within apoptotic process	IEA Inferred from Electronic Annotation more info
involved_in axon guidance	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within blood vessel development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within blood vessel remodeling	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within cardiac muscle cell differentiation	IGI Inferred from Genetic Interaction more info	PubMed
involved_in cardiac muscle cell differentiation	NAS Non-traceable Author Statement more info	PubMed
acts_upstream_of_or_within cardiac muscle hypertrophy in response to stress	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within cardiac ventricle formation	IGI Inferred from Genetic Interaction more info	PubMed
involved_in cardiac ventricle formation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within cartilage morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cell differentiation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within cell fate commitment	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cell morphogenesis involved in neuron differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of cell proliferation in bone marrow	IGI Inferred from Genetic Interaction more info	PubMed
involved_in cellular response to calcium ion	IDA Inferred from Direct Assay more info	PubMed
involved_in cellular response to fluid shear stress	IDA Inferred from Direct Assay more info	PubMed
involved_in cellular response to growth factor stimulus	ISO Inferred from Sequence Orthology more info
involved_in cellular response to lipopolysaccharide	IDA Inferred from Direct Assay more info	PubMed
involved_in cellular response to parathyroid hormone stimulus	ISO Inferred from Sequence Orthology more info
involved_in cellular response to retinoic acid	ISO Inferred from Sequence Orthology more info
involved_in cellular response to transforming growth factor beta stimulus	ISO Inferred from Sequence Orthology more info
involved_in cellular response to trichostatin A	IDA Inferred from Direct Assay more info	PubMed
involved_in cellular response to xenobiotic stimulus	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within chondrocyte differentiation	IGI Inferred from Genetic Interaction more info	PubMed
involved_in embryonic heart tube development	IGI Inferred from Genetic Interaction more info	PubMed
involved_in embryonic heart tube development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within embryonic skeletal system morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within embryonic viscerocranium morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within endochondral ossification	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within endochondral ossification	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in epithelial cell proliferation involved in renal tubule morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in excitatory postsynaptic potential	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in gene expression	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in germinal center formation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in glomerulus morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in heart development	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within heart development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in heart looping	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in humoral immune response	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in learning or memory	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in melanocyte differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within monocyte differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within multicellular organism development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within muscle cell fate determination	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of blood vessel endothelial cell migration	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of epithelial cell proliferation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of gene expression	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of neuron apoptotic process	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of neuron apoptotic process	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of ossification	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II	IGI Inferred from Genetic Interaction more info	PubMed
involved_in negative regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of vascular associated smooth muscle cell migration	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of vascular associated smooth muscle cell proliferation	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of vascular endothelial cell proliferation	ISO Inferred from Sequence Orthology more info
involved_in nephron tubule epithelial cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within nervous system development	IEA Inferred from Electronic Annotation more info
involved_in neural crest cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in neuron development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in neuron differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in neuron migration	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in osteoblast differentiation	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within osteoblast differentiation	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within outflow tract morphogenesis	IGI Inferred from Genetic Interaction more info	PubMed
involved_in platelet formation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of B cell proliferation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within positive regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within positive regulation of DNA-templated transcription	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of DNA-templated transcription	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of MAPK cascade	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of alkaline phosphatase activity	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of behavioral fear response	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of bone mineralization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of cardiac muscle cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of cardiac muscle cell differentiation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of cardiac muscle cell proliferation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of cardiac muscle hypertrophy	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of cell proliferation in bone marrow	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of gene expression	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of gene expression	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of gene expression	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of macrophage apoptotic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of myoblast differentiation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of neuron differentiation	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of osteoblast differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of skeletal muscle cell differentiation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of skeletal muscle tissue development	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in primary heart field specification	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of DNA-templated transcription	ISO Inferred from Sequence Orthology more info
involved_in regulation of dendritic spine development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of germinal center formation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of megakaryocyte differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of neuron apoptotic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of neurotransmitter secretion	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of sarcomere organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of synapse assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of synaptic activity	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of synaptic plasticity	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of synaptic transmission, glutamatergic	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in renal tubule morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to ischemia	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within roof of mouth development	IGI Inferred from Genetic Interaction more info	PubMed
involved_in secondary heart field specification	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in semaphorin-plexin signaling pathway involved in axon guidance	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in sinoatrial valve morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within skeletal muscle cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in skeletal muscle cell differentiation	NAS Non-traceable Author Statement more info	PubMed
acts_upstream_of_or_within skeletal muscle tissue development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within smooth muscle cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in sympathetic neuron axon guidance	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in transdifferentiation	ISO Inferred from Sequence Orthology more info
involved_in ventricular cardiac muscle cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in intracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info
located_in nuclear speck	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	TAS Traceable Author Statement more info
located_in nucleus	IC Inferred by Curator more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISO Inferred from Sequence Orthology more info
part_of protein-containing complex	ISO Inferred from Sequence Orthology more info
located_in sarcomere	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: myocyte-specific enhancer factor 2C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001170537.2 → NP_001164008.1 myocyte-specific enhancer factor 2C isoform 1

See identical proteins and their annotated locations for NP_001164008.1

Status: VALIDATED

Description

Transcript Variant: This variant (1) lacks an alternate in-frame exon in the central coding region, compared to variant 3, resulting in an isoform (1) that is shorter than isoform 3.

Source sequence(s)

AC107750, CT025631, CU074400

Consensus CDS

CCDS49320.1

UniProtKB/TrEMBL

A0A0G2JDT0, Q3V1B5

Related

ENSMUSP00000143315.2, ENSMUST00000199450.5

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
NM_001347564.2 → NP_001334493.1 myocyte-specific enhancer factor 2C isoform 3

Status: VALIDATED

Description

Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3). Variants 3, 4 and 5 all encode isoform 3.

Source sequence(s)

AC107750, CT025631, CU074400

Consensus CDS

CCDS84042.1

UniProtKB/Swiss-Prot

Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20

UniProtKB/TrEMBL

A0A0G2JDT0

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
NM_001347566.2 → NP_001334495.1 myocyte-specific enhancer factor 2C isoform 3

Status: VALIDATED

Description

Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 3. Variants 3, 4 and 5 all encode isoform 3.

Source sequence(s)

CT025631, CU074400

Consensus CDS

CCDS84042.1

UniProtKB/Swiss-Prot

Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20

UniProtKB/TrEMBL

A0A0G2JDT0

Related

ENSMUSP00000143401.2, ENSMUST00000199019.5

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
NM_001347567.2 → NP_001334496.1 myocyte-specific enhancer factor 2C isoform 3

Status: VALIDATED

Description

Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 3. Variants 3, 4 and 5 all encode isoform 3.

Source sequence(s)

CT025631, CU074400

Consensus CDS

CCDS84042.1

UniProtKB/Swiss-Prot

Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20

UniProtKB/TrEMBL

A0A0G2JDT0

Related

ENSMUSP00000143212.2, ENSMUST00000199105.5

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
NM_001347568.2 → NP_001334497.1 myocyte-specific enhancer factor 2C isoform 4

Status: VALIDATED

Description

Transcript Variant: This variant (6) differs in the 5' UTR and uses an alternate in-frame exon in the 5' coding region, compared to variant 3. The encoded isoform (4) is shorter than isoform 3. Both variants 6 and 7 encode isoform 4.

Source sequence(s)

CT025631, CU074400

Consensus CDS

CCDS84045.1

UniProtKB/TrEMBL

A0A0G2JDT0

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:96 → 150

HJURP_C; Holliday junction regulator protein family C-terminal repeat
NM_001347569.2 → NP_001334498.1 myocyte-specific enhancer factor 2C isoform 4

Status: VALIDATED

Description

Transcript Variant: This variant (7) differs in the 5' UTR and uses an alternate in-frame exon in the 5' coding region, compared to variant 3. The encoded isoform (4) is shorter than isoform 3. Both variants 6 and 7 encode isoform 4.

Source sequence(s)

CT025631, CU074400

Consensus CDS

CCDS84045.1

UniProtKB/TrEMBL

A0A0G2JDT0

Related

ENSMUSP00000138826.3, ENSMUST00000185052.6

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:96 → 150

HJURP_C; Holliday junction regulator protein family C-terminal repeat
NM_001347571.2 → NP_001334500.1 myocyte-specific enhancer factor 2C isoform 5

Status: VALIDATED

Description

Transcript Variant: This variant (8) uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.

Source sequence(s)

AC107750, CT025631, CU074400

Consensus CDS

CCDS84043.1

UniProtKB/TrEMBL

A0A0G2JE18

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
NM_001347572.2 → NP_001334501.1 myocyte-specific enhancer factor 2C isoform 5

Status: VALIDATED

Description

Transcript Variant: This variant (9) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.

Source sequence(s)

AC107750, CT025631, CU074400

Consensus CDS

CCDS84043.1

UniProtKB/TrEMBL

A0A0G2JE18

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
NM_001347573.2 → NP_001334502.1 myocyte-specific enhancer factor 2C isoform 5

Status: VALIDATED

Description

Transcript Variant: This variant (10) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.

Source sequence(s)

AC107750, CT025631, CU074400

Consensus CDS

CCDS84043.1

UniProtKB/TrEMBL

A0A0G2JE18

Related

ENSMUSP00000142595.2, ENSMUST00000199210.5

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
NM_001347574.2 → NP_001334503.1 myocyte-specific enhancer factor 2C isoform 5

Status: VALIDATED

Description

Transcript Variant: This variant (11) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.

Source sequence(s)

AC107750, CT025631, CU074400

Consensus CDS

CCDS84043.1

UniProtKB/TrEMBL

A0A0G2JE18

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
NM_001347575.2 → NP_001334504.1 myocyte-specific enhancer factor 2C isoform 5

Status: VALIDATED

Description

Transcript Variant: This variant (12) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.

Source sequence(s)

CT025631, CU074400

Consensus CDS

CCDS84043.1

UniProtKB/TrEMBL

A0A0G2JE18

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
NM_001347576.2 → NP_001334505.1 myocyte-specific enhancer factor 2C isoform 5

Status: VALIDATED

Description

Transcript Variant: This variant (13) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.

Source sequence(s)

CT025631, CU074400

Consensus CDS

CCDS84043.1

UniProtKB/TrEMBL

A0A0G2JE18

Related

ENSMUSP00000143420.2, ENSMUST00000197681.5

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
NM_001347577.2 → NP_001334506.1 myocyte-specific enhancer factor 2C isoform 5

Status: VALIDATED

Description

Transcript Variant: This variant (14) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.

Source sequence(s)

CT025631, CU074400

Consensus CDS

CCDS84043.1

UniProtKB/TrEMBL

A0A0G2JE18

Related

ENSMUSP00000143227.2, ENSMUST00000197146.5

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
NM_001347578.2 → NP_001334507.1 myocyte-specific enhancer factor 2C isoform 6

Status: VALIDATED

Description

Transcript Variant: This variant (15) differs in the 5' UTR, lacks an in-frame exon in the central coding region, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3. The encoded isoform (6) is shorter than isoform 3.

Source sequence(s)

CT025631, CU074400

Consensus CDS

CCDS84044.1

UniProtKB/TrEMBL

A0A0G2JE18, A0A0G2JEC2

Related

ENSMUSP00000142714.2, ENSMUST00000199432.5

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
NM_001347579.2 → NP_001334508.1 myocyte-specific enhancer factor 2C isoform 7

Status: VALIDATED

Description

Transcript Variant: This variant (16) differs in the 5' UTR, and uses an alternate splice site that results in a frameshift in the 3' coding region, compared to variant 3. The encoded isoform (7) has a distinct C-terminus and is shorter than isoform 3. Both variants 16 and 17 encode isoform 7.

Source sequence(s)

AC107750, CT025631, CU074400

UniProtKB/TrEMBL

A0A0G2JDQ1
NM_001347580.2 → NP_001334509.1 myocyte-specific enhancer factor 2C isoform 7

Status: VALIDATED

Description

Transcript Variant: This variant (17) differs in the 5' UTR, and uses an alternate splice site that results in a frameshift in the 3' coding region, compared to variant 3. The encoded isoform (7) has a distinct C-terminus and is shorter than isoform 3. Both variants 16 and 17 encode isoform 7.

Source sequence(s)

CT025631, CU074400

UniProtKB/TrEMBL

A0A0G2JDQ1

Related

ENSMUSP00000142456.2, ENSMUST00000197722.5
NM_001347581.2 → NP_001334510.1 myocyte-specific enhancer factor 2C isoform 8

Status: VALIDATED

Description

Transcript Variant: This variant (18) differs in the 5' UTR, lacks an in-frame exon in the central coding region, and uses an alternate splice site that results in a frameshift in the 3' coding region, compared to variant 3. The encoded isoform (8) has a distinct C-terminus and is shorter than isoform 3.

Source sequence(s)

CT025631, CU074400

UniProtKB/TrEMBL

A0A0G2JDQ1
NM_025282.4 → NP_079558.1 myocyte-specific enhancer factor 2C isoform 2

See identical proteins and their annotated locations for NP_079558.1

Status: VALIDATED

Description

Transcript Variant: This variant (2) contains an alternate in-frame exon in the 5' coding region, lacks an in-frame exon in the central coding region, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3. The encoded isoform (2) is shorter than isoform 3.

Source sequence(s)

AC107750, CT025631, CU074400

Consensus CDS

CCDS26664.1

UniProtKB/TrEMBL

A0A0G2JE18

Related

ENSMUSP00000143742.2, ENSMUST00000198199.5

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:96 → 150

HJURP_C; Holliday junction regulator protein family C-terminal repeat

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000079.7 Reference GRCm39 C57BL/6J

Range

83652136..83815197

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006517123.4 → XP_006517186.1 myocyte-specific enhancer factor 2C isoform X1

See identical proteins and their annotated locations for XP_006517186.1

UniProtKB/Swiss-Prot

Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20

UniProtKB/TrEMBL

A0A0G2JDT0

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
XM_036157888.1 → XP_036013781.1 myocyte-specific enhancer factor 2C isoform X4

UniProtKB/TrEMBL

A0A0G2JDT0, A0A0H2UKB6

Related

ENSMUSP00000005722.9, ENSMUST00000005722.14

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:96 → 150

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_036157891.1 → XP_036013784.1 myocyte-specific enhancer factor 2C isoform X6

UniProtKB/TrEMBL

A0A0G2JE18, A0A0G2JEC2

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
XM_036157892.1 → XP_036013785.1 myocyte-specific enhancer factor 2C isoform X6

UniProtKB/TrEMBL

A0A0G2JE18, A0A0G2JEC2

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
XM_030247172.2 → XP_030103032.1 myocyte-specific enhancer factor 2C isoform X1

UniProtKB/Swiss-Prot

Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20

UniProtKB/TrEMBL

A0A0G2JDT0

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
XM_036157887.1 → XP_036013780.1 myocyte-specific enhancer factor 2C isoform X2

UniProtKB/TrEMBL

A0A0G2JDT0

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:96 → 150

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_017315405.3 → XP_017170894.1 myocyte-specific enhancer factor 2C isoform X1

UniProtKB/Swiss-Prot

Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20

UniProtKB/TrEMBL

A0A0G2JDT0

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
XM_036157895.1 → XP_036013788.1 myocyte-specific enhancer factor 2C isoform X6

UniProtKB/TrEMBL

A0A0G2JE18, A0A0G2JEC2

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
XM_030247175.2 → XP_030103035.1 myocyte-specific enhancer factor 2C isoform X3

UniProtKB/TrEMBL

A0A0G2JDT0, Q3V1B5

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
XM_011244492.4 → XP_011242794.1 myocyte-specific enhancer factor 2C isoform X1

See identical proteins and their annotated locations for XP_011242794.1

UniProtKB/Swiss-Prot

Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20

UniProtKB/TrEMBL

A0A0G2JDT0

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
XM_030247177.2 → XP_030103037.1 myocyte-specific enhancer factor 2C isoform X8

UniProtKB/TrEMBL

A0A0G2JE18

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
XM_030247176.2 → XP_030103036.1 myocyte-specific enhancer factor 2C isoform X3

UniProtKB/TrEMBL

A0A0G2JDT0, Q3V1B5

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
XM_006517127.5 → XP_006517190.1 myocyte-specific enhancer factor 2C isoform X3

See identical proteins and their annotated locations for XP_006517190.1

UniProtKB/TrEMBL

A0A0G2JDT0, Q3V1B5

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
XM_011244495.4 → XP_011242797.1 myocyte-specific enhancer factor 2C isoform X9

UniProtKB/TrEMBL

A0A0G2JDT0, A0A0H2UH28

Related

ENSMUSP00000132547.3, ENSMUST00000163888.8

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:116 → 170

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_006517126.4 → XP_006517189.1 myocyte-specific enhancer factor 2C isoform X2

See identical proteins and their annotated locations for XP_006517189.1

UniProtKB/TrEMBL

A0A0G2JDT0

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:96 → 150

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_036157889.1 → XP_036013782.1 myocyte-specific enhancer factor 2C isoform X5

UniProtKB/TrEMBL

A0A0G2JE18

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:96 → 150

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_006517128.5 → XP_006517191.1 myocyte-specific enhancer factor 2C isoform X4

UniProtKB/TrEMBL

A0A0G2JDT0, A0A0H2UKB6

Related

ENSMUSP00000142487.2, ENSMUST00000198217.5

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:96 → 150

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_006517130.4 → XP_006517193.1 myocyte-specific enhancer factor 2C isoform X6

See identical proteins and their annotated locations for XP_006517193.1

UniProtKB/TrEMBL

A0A0G2JE18, A0A0G2JEC2

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
XM_006517132.5 → XP_006517195.1 myocyte-specific enhancer factor 2C isoform X7

See identical proteins and their annotated locations for XP_006517195.1

UniProtKB/TrEMBL

A0A0G2JE18

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:96 → 150

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_006517124.5 → XP_006517187.1 myocyte-specific enhancer factor 2C isoform X1

See identical proteins and their annotated locations for XP_006517187.1

UniProtKB/Swiss-Prot

Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20

UniProtKB/TrEMBL

A0A0G2JDT0

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
XM_036157893.1 → XP_036013786.1 myocyte-specific enhancer factor 2C isoform X6

UniProtKB/TrEMBL

A0A0G2JE18, A0A0G2JEC2

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
XM_036157890.1 → XP_036013783.1 myocyte-specific enhancer factor 2C isoform X8

UniProtKB/TrEMBL

A0A0G2JE18

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
XM_036157894.1 → XP_036013787.1 myocyte-specific enhancer factor 2C isoform X6

UniProtKB/TrEMBL

A0A0G2JE18, A0A0G2JEC2

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
XM_036157886.1 → XP_036013779.1 myocyte-specific enhancer factor 2C isoform X1

UniProtKB/Swiss-Prot

Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20

UniProtKB/TrEMBL

A0A0G2JDT0

Conserved Domains (2) summary

COG5068
Location:1 → 245

ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...