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    Dhrs13 dehydrogenase/reductase 13 [ Mus musculus (house mouse) ]

    Gene ID: 70451, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Dhrs13provided by MGI
    Official Full Name
    dehydrogenase/reductase 13provided by MGI
    Primary source
    MGI:MGI:1917701
    See related
    Ensembl:ENSMUSG00000020834 AllianceGenome:MGI:1917701
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2610209N15Rik
    Summary
    Predicted to enable NADP-retinol dehydrogenase activity. Predicted to be involved in retinal metabolic process. Predicted to be located in extracellular region. Predicted to be active in mitochondrial inner membrane. Orthologous to human DHRS13 (dehydrogenase/reductase 13). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 9.9), adrenal adult (RPKM 9.8) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    11 B5; 11 46.74 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (77923139..77928690)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (78032313..78037864)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_30082 Neighboring gene predicted gene, 53689 Neighboring gene PHD finger protein 12 Neighboring gene predicted gene, 51908 Neighboring gene STARR-positive B cell enhancer ABC_E10693 Neighboring gene dehydrogenase/reductase 13, opposite strand Neighboring gene flotillin 2 Neighboring gene predicted gene, 57805 Neighboring gene microRNA 144

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Genome-wide identification of Smad/Foxh1 targets reveals a role for Foxh1 in retinoic acid regulation and forebrain development. Silvestri C, et al. Dev Cell, 2008 Mar. PMID 18331719
    2. New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules. Das R, et al. J Cell Sci, 2019 Jun 17. PMID 31138677, Free PMC Article
    3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    4. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Zhang T, et al. Sci Rep, 2017 Apr 5. PMID 28378742, Free PMC Article
    5. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC141618

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    dehydrogenase/reductase SDR family member 13
    Names
    androgen-regulated short-chain dehydrogenase/reductase 1; prostate short-chain dehydrogenase reductase 1; likely ortholog of mouse cell line MC/9.IL4 derived transcript 1; CGI-82 protein; HCV core-binding protein
    dehydrogenase/reductase (SDR family) member 13
    short chain dehydrogenase/reductase family 7C member 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_183286.2 → NP_899109.2  dehydrogenase/reductase SDR family member 13 precursor

      See identical proteins and their annotated locations for NP_899109.2

      Status: VALIDATED

      Source sequence(s)
      AK046465, BB637905
      Consensus CDS
      CCDS36236.1
      UniProtKB/Swiss-Prot
      Q14BH2, Q5SS80, Q8BMX8
      UniProtKB/TrEMBL
      B0QZT2
      Related
      ENSMUSP00000021187.6, ENSMUST00000021187.12
      Conserved Domains (2) summary
      cd05327
      Location:36 → 304
      retinol-DH_like_SDR_c_like; retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs
      PRK06197
      Location:31 → 312
      PRK06197; short chain dehydrogenase; Provisional

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      77923139..77928690
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5SS80.1 GenPept UniProtKB/Swiss-Prot:Q5SS80

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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