Lypd2 Ly6/Plaur domain containing 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Lypd2provided by MGI
Official Full Name: Ly6/Plaur domain containing 2provided by MGI
Primary source: MGI:MGI:1915561
See related: Ensembl:ENSMUSG00000022595 AllianceGenome:MGI:1915561
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: VLL; Lypdc2; 0610005K03Rik
Summary: Predicted to be located in plasma membrane. Predicted to be anchored component of membrane. Is expressed in future spinal cord; hindbrain; midbrain; and telencephalon. Orthologous to human LYPD2 (LY6/PLAUR domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in lung adult (RPKM 49.0), kidney adult (RPKM 10.0) and 1 other tissue See more
Orthologs: human all
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Genomic context

Location:: 15 D3; 15 34.26 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	15	NC_000081.7 (74604095..74606644, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	15	NC_000081.6 (74732246..74734795, complement)

Chromosome 15 - NC_000081.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (1) 1 citation
Endonuclease-mediated (1)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in side of membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ly6/PLAUR domain-containing protein 2

Names: H8C4 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_026671.1 → NP_080947.1 ly6/PLAUR domain-containing protein 2 precursor

See identical proteins and their annotated locations for NP_080947.1

Status: PROVISIONAL

Source sequence(s)

BC099511

Consensus CDS

CCDS27529.1

UniProtKB/Swiss-Prot

A2RT83, Q9DD23

Related

ENSMUSP00000023260.4, ENSMUST00000023260.5

Conserved Domains (1) summary

cd00117
Location:23 → 102

LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000081.7 Reference GRCm39 C57BL/6J

Range

74604095..74606644 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006521312.1 → XP_006521375.1 ly6/PLAUR domain-containing protein 2 isoform X1

See identical proteins and their annotated locations for XP_006521375.1

UniProtKB/Swiss-Prot

A2RT83, Q9DD23

Conserved Domains (1) summary

cd00117
Location:23 → 102

LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...