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    Tspan31 tetraspanin 31 [ Mus musculus (house mouse) ]

    Gene ID: 67125, updated on 24-Apr-2024

    Summary

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    Official Symbol
    Tspan31provided by MGI
    Official Full Name
    tetraspanin 31provided by MGI
    Primary source
    MGI:MGI:1914375
    See related
    Ensembl:ENSMUSG00000006736 AllianceGenome:MGI:1914375
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sas; 2700085A14Rik
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in brain. Orthologous to human TSPAN31 (tetraspanin 31). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in liver adult (RPKM 83.9), placenta adult (RPKM 37.9) and 27 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tspan31 in Genome Data Viewer
    Location:
    10 D3; 10 74.5 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (126903156..126906977, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (127067287..127070972, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 27, subfamily b, polypeptide 1 Neighboring gene membrane associated ring-CH-type finger 9 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:126500339-126500526 Neighboring gene RIKEN cDNA A730063M14 gene Neighboring gene STARR-positive B cell enhancer ABC_E582 Neighboring gene cyclin dependent kinase 4 Neighboring gene ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 Neighboring gene amplified in osteosarcoma Neighboring gene predicted gene, 40799

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Appearance of new tetraspanin genes during vertebrate evolution. Garcia-España A, et al. Genomics, 2008 Apr. PMID 18291621
    2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    3. A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Thompson CL, et al. Neuron, 2014 Jul 16. PMID 24952961, Free PMC Article
    4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tetraspanin-31
    Names
    sarcoma amplified sequence
    sarcoma-amplified sequence homolog
    tspan-31

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001429425.1 → NP_001416354.1  tetraspanin-31 isoform b precursor

      Status: VALIDATED

      Source sequence(s)
      AC134329

    2. NM_001429426.1 → NP_001416355.1  tetraspanin-31 isoform b precursor

      Status: VALIDATED

      Source sequence(s)
      AC134329

    3. NM_025982.4 → NP_080258.1  tetraspanin-31 isoform a

      See identical proteins and their annotated locations for NP_080258.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (a).
      Source sequence(s)
      AC134329
      Consensus CDS
      CCDS24227.1
      UniProtKB/Swiss-Prot
      Q9CQ88, Q9CUY7
      Related
      ENSMUSP00000057751.5, ENSMUST00000060991.6
      Conserved Domains (1) summary
      pfam00335
      Location:8 → 199
      Tetraspannin; Tetraspanin family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      126903156..126906977 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030245229.2 → XP_030101089.1  tetraspanin-31 isoform X1

      Conserved Domains (1) summary
      pfam00335
      Location:2 → 118
      Tetraspannin; Tetraspanin family

    2. XM_030245230.1 → XP_030101090.1  tetraspanin-31 isoform X1

      Conserved Domains (1) summary
      pfam00335
      Location:2 → 118
      Tetraspannin; Tetraspanin family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CQ88.1 GenPept UniProtKB/Swiss-Prot:Q9CQ88

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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