Ces2b carboxyesterase 2B [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ces2bprovided by MGI
Official Full Name: carboxyesterase 2Bprovided by MGI
Primary source: MGI:MGI:2448547
See related: Ensembl:ENSMUSG00000050097 AllianceGenome:MGI:2448547
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Predicted to enable carboxylic ester hydrolase activity. Predicted to be involved in prostaglandin metabolic process. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in liver lobe and naris. Orthologous to human CES2 (carboxylesterase 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in duodenum adult (RPKM 7.6), stomach adult (RPKM 5.2) and 8 other tissues See more
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Genomic context

Location:: 8 D3; 8 53.04 cM

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	8	NC_000074.7 (105555130..105566725)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	8	NC_000074.6 (104828494..104840093)

Chromosome 8 - NC_000074.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

General gene information

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Markers

px-65a8 (e-PCR)
- UniSTS:258110

px-35d2 (e-PCR)
- UniSTS:257633

px-45f3 (e-PCR)
- UniSTS:258415

px-72g5 (e-PCR)
- UniSTS:258181

px-60g6 (e-PCR)
- UniSTS:258437

px-8b4 (e-PCR)
- UniSTS:258464

px-24g4 (e-PCR)
- UniSTS:257458

px-61b6 (e-PCR)
- UniSTS:258032

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables carboxylesterase activity	ISO Inferred from Sequence Orthology more info
enables carboxylic ester hydrolase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in prostaglandin metabolic process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in intracellular membrane-bounded organelle	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: carboxyesterase 2B

NP_937814.1

EC 3.1.1.1

XP_006530948.1

EC 3.1.1.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.