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    MGAT5 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase [ Homo sapiens (human) ]

    Gene ID: 4249, updated on 3-Apr-2024

    Summary

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    Official Symbol
    MGAT5provided by HGNC
    Official Full Name
    alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferaseprovided by HGNC
    Primary source
    HGNC:HGNC:7049
    See related
    Ensembl:ENSG00000152127 MIM:601774; AllianceGenome:HGNC:7049
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    GNT-V; GNT-VA; MGAT5A; glcNAc-T V
    Summary
    The protein encoded by this gene belongs to the glycosyltransferase family. It catalyzes the addition of beta-1,6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the activity of this enzyme has been correlated with the progression of invasive malignancies. [provided by RefSeq, Oct 2011]
    Expression
    Ubiquitous expression in heart (RPKM 14.6), lymph node (RPKM 12.4) and 24 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See MGAT5 in Genome Data Viewer
    Location:
    2q21.2-q21.3
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (134119935..134454621)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (134559395..134894193)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (134877506..135212192)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105373627 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16542 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr2:134742538-134743737 Neighboring gene uncharacterized LOC105373628 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16543 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr2:134821977-134822608 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16544 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:134864951-134865484 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:134866541-134867202 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:134867203-134867862 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11972 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11974 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11973 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11971 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11975 Neighboring gene NANOG hESC enhancer GRCh37_chr2:134891163-134891785 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:134891786-134892407 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_52669 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16545 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:134915432-134916037 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:134916038-134916642 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16546 Neighboring gene microRNA 3679 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_52692 Neighboring gene NANOG hESC enhancer GRCh37_chr2:134960700-134961201 Neighboring gene Sharpr-MPRA regulatory region 5769 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11976 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16547 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:135002234-135002734 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:135002735-135003235 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16549 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16548 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16550 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16551 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16552 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16553 Neighboring gene RNA, 5S ribosomal pseudogene 104 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16554 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16555 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16556 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16557 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16558 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16559 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16560 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16561 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:135129934-135130438 Neighboring gene epididymal protein 3C, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16562 Neighboring gene Sharpr-MPRA regulatory region 6492 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:135201292-135201792 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:135217811-135218312 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:135218313-135218812 Neighboring gene Sharpr-MPRA regulatory region 15464 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:135240067-135240597 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:135240598-135241127 Neighboring gene uncharacterized LOC124906076 Neighboring gene transmembrane protein 163 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:135293574-135294074 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:135318760-135318939 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16563 Neighboring gene MPRA-validated peak3868 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16564 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11977 Neighboring gene uncharacterized LOC105373629 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11978 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr2:135478596-135479795

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Aberrant N-glycosylation in cancer: MGAT5 and β1,6-GlcNAc branched N-glycans as critical regulators of tumor development and progression. de-Souza-Ferreira M, et al. Cell Oncol (Dordr), 2023 Jun. PMID 36689079
    2. N-acetylglucosaminyltransferase-V requires a specific noncatalytic luminal domain for its activity toward glycoprotein substrates. Osuka RF, et al. J Biol Chem, 2022 Mar. PMID 35104505, Free PMC Article
    3. Glioma stem cells invasive phenotype at optimal stiffness is driven by MGAT5 dependent mechanosensing. Marhuenda E, et al. J Exp Clin Cancer Res, 2021 Apr 24. PMID 33894774, Free PMC Article
    4. Recognition of glycan and protein substrates by N-acetylglucosaminyltransferase-V. Hirata T, et al. Biochim Biophys Acta Gen Subj, 2020 Dec. PMID 32890705
    5. Genetic Variants of the MGAT5 Gene Are Functionally Implicated in the Modulation of T Cells Glycosylation and Plasma IgG Glycome Composition in Ulcerative Colitis. Pereira MS, et al. Clin Transl Gastroenterol, 2020 Apr. PMID 32352685, Free PMC Article

    See all (90) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. GnT-V-mediated aberrant N-glycosylation of TIMP-1 promotes diabetic retinopathy progression.
      Title: GnT-V-mediated aberrant N-glycosylation of TIMP-1 promotes diabetic retinopathy progression.
    2. Aberrant N-glycosylation in cancer: MGAT5 and beta1,6-GlcNAc branched N-glycans as critical regulators of tumor development and progression.
      Title: Aberrant N-glycosylation in cancer: MGAT5 and β1,6-GlcNAc branched N-glycans as critical regulators of tumor development and progression.
    3. N-acetylglucosaminyltransferase-V requires a specific noncatalytic luminal domain for its activity toward glycoprotein substrates.
      Title: N-acetylglucosaminyltransferase-V requires a specific noncatalytic luminal domain for its activity toward glycoprotein substrates.
    4. Glioma stem cells invasive phenotype at optimal stiffness is driven by MGAT5 dependent mechanosensing.
      Title: Glioma stem cells invasive phenotype at optimal stiffness is driven by MGAT5 dependent mechanosensing.
    5. The polymorphisms of FGFR2 and MGAT5 affect the susceptibility to COPD in the Chinese people.
      Title: The polymorphisms of FGFR2 and MGAT5 affect the susceptibility to COPD in the Chinese people.
    6. Nglycosylation and receptor tyrosine kinase signaling affect claudin3 levels in colorectal cancer cells.
      Title: N‑glycosylation and receptor tyrosine kinase signaling affect claudin‑3 levels in colorectal cancer cells.
    7. Genetic Variants of the MGAT5 Gene Are Functionally Implicated in the Modulation of T Cells Glycosylation and Plasma IgG Glycome Composition in Ulcerative Colitis.
      Title: Genetic Variants of the MGAT5 Gene Are Functionally Implicated in the Modulation of T Cells Glycosylation and Plasma IgG Glycome Composition in Ulcerative Colitis.
    8. Recognition of glycan and protein substrates by N-acetylglucosaminyltransferase-V.
      Title: Recognition of glycan and protein substrates by N-acetylglucosaminyltransferase-V.
    9. Results suggest increased post-translational modification of RPTPmu N-glycans by GnT-V attenuates its tyrosine phosphatase activity and promotes glioma cell migration through PLCgamma-PKC pathways.
      Title: β1,6 GlcNAc branches-modified protein tyrosine phosphatase Mu attenuates its tyrosine phosphatase activity and promotes glioma cell migration through PLCγ-PKC pathways.
    10. GnT-V enhances gemcitabine chemosensitivity via modulation of human ENT1 N-glycosylation and transport activity in T24cells, providing new insights into how N-glycosylation drives antitumor drug sensitivity during chemotherapy for patients with cancer.
      Title: GnT-V promotes chemosensitivity to gemcitabine in bladder cancer cells through β1,6 GlcNAc branch modification of human equilibrative nucleoside transporter 1.
    Submit: New GeneRIF Correction See all GeneRIFs (68)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
    EBI GWAS Catalog
    MGAT5 alters the severity of multiple sclerosis.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ31899, FLJ43217, DKFZp686B24166

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity TAS
    Traceable Author Statement
    more info
    		  
    enables manganese ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein phosphatase inhibitor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of protein tyrosine phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of cell migration IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of receptor signaling pathway via STAT IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein N-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein N-linked glycosylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein N-linked glycosylation via asparagine IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in viral protein processing TAS
    Traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in Golgi membrane TAS
    Traceable Author Statement
    more info
    		  
    located_in extracellular exosome HDA PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A
    Names
    N-acetylglucosaminyl-transferase V
    alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase V
    mannoside acetylglucosaminyltransferase 5
    mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
    NP_001358386.1
    NP_002401.1
    XP_005263726.1
    XP_006712597.1
    XP_011509501.1
    XP_011509503.1
    XP_011509504.1
    XP_016859636.1
    XP_016859637.1
    XP_016859638.1
    XP_047300350.1
    XP_047300351.1
    XP_047300352.1
    XP_047300353.1
    XP_047300354.1
    XP_047300355.1
    XP_047300356.1
    XP_047300357.1
    XP_047300358.1
    XP_047300359.1
    XP_047300360.1
    XP_047300361.1
    XP_047300362.1
    XP_054198083.1
    XP_054198084.1
    XP_054198085.1
    XP_054198086.1
    XP_054198087.1
    XP_054198088.1
    XP_054198089.1
    XP_054198090.1
    XP_054198091.1
    XP_054198092.1
    XP_054198093.1
    XP_054198094.1
    XP_054198095.1
    XP_054198096.1
    XP_054198097.1
    XP_054198098.1
    XP_054198099.1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_030324.2 RefSeqGene

      Range
      139139..339688
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001371457.1 → NP_001358386.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

      Status: REVIEWED

      Source sequence(s)
      AC013276, AC013718, AC016906, AC092623
      Consensus CDS
      CCDS2171.1
      UniProtKB/Swiss-Prot
      D3DP70, Q09328
      Related
      ENSP00000386377.1, ENST00000409645.5
      Conserved Domains (2) summary
      pfam15027
      Location:7 → 138
      DUF4525; Domain of unknown function (DUF4525)
      pfam15024
      Location:172 → 726
      Glyco_transf_18; Glycosyltransferase family 18

    2. NM_002410.5 → NP_002401.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

      See identical proteins and their annotated locations for NP_002401.1

      Status: REVIEWED

      Source sequence(s)
      AC013718, AC016906, AK056461, BU191961, BX647087, D17716, DB223638, DB237089
      Consensus CDS
      CCDS2171.1
      UniProtKB/Swiss-Prot
      D3DP70, Q09328
      Related
      ENSP00000281923.2, ENST00000281923.4
      Conserved Domains (2) summary
      pfam15027
      Location:7 → 138
      DUF4525; Domain of unknown function (DUF4525)
      pfam15024
      Location:172 → 726
      Glyco_transf_18; Glycosyltransferase family 18

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      134119935..134454621
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006712534.4 → XP_006712597.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      See identical proteins and their annotated locations for XP_006712597.1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328
      Conserved Domains (2) summary
      pfam15027
      Location:7 → 138
      DUF4525; Domain of unknown function (DUF4525)
      pfam15024
      Location:172 → 726
      Glyco_transf_18; Glycosyltransferase family 18

    2. XM_047444397.1 → XP_047300353.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    3. XM_047444400.1 → XP_047300356.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    4. XM_047444395.1 → XP_047300351.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    5. XM_047444401.1 → XP_047300357.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    6. XM_047444399.1 → XP_047300355.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    7. XM_017004147.3 → XP_016859636.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328
      Conserved Domains (2) summary
      pfam15027
      Location:7 → 138
      DUF4525; Domain of unknown function (DUF4525)
      pfam15024
      Location:172 → 726
      Glyco_transf_18; Glycosyltransferase family 18

    8. XM_047444396.1 → XP_047300352.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    9. XM_005263669.6 → XP_005263726.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      See identical proteins and their annotated locations for XP_005263726.1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328
      Conserved Domains (2) summary
      pfam15027
      Location:7 → 138
      DUF4525; Domain of unknown function (DUF4525)
      pfam15024
      Location:172 → 726
      Glyco_transf_18; Glycosyltransferase family 18

    10. XM_047444406.1 → XP_047300362.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X2

    11. XM_017004149.2 → XP_016859638.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X2

      UniProtKB/TrEMBL
      Q53SM9
      Conserved Domains (2) summary
      pfam15024
      Location:172 → 460
      Glyco_transf_18; Glycosyltransferase family 18
      pfam15027
      Location:3 → 138
      DUF4525; Domain of unknown function (DUF4525)

    12. XM_047444402.1 → XP_047300358.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    13. XM_047444404.1 → XP_047300360.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    14. XM_017004148.2 → XP_016859637.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328
      Conserved Domains (2) summary
      pfam15027
      Location:7 → 138
      DUF4525; Domain of unknown function (DUF4525)
      pfam15024
      Location:172 → 726
      Glyco_transf_18; Glycosyltransferase family 18

    15. XM_047444403.1 → XP_047300359.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    16. XM_011511201.3 → XP_011509503.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      See identical proteins and their annotated locations for XP_011509503.1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328
      Conserved Domains (2) summary
      pfam15027
      Location:7 → 138
      DUF4525; Domain of unknown function (DUF4525)
      pfam15024
      Location:172 → 726
      Glyco_transf_18; Glycosyltransferase family 18

    17. XM_011511199.3 → XP_011509501.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      See identical proteins and their annotated locations for XP_011509501.1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328
      Conserved Domains (2) summary
      pfam15027
      Location:7 → 138
      DUF4525; Domain of unknown function (DUF4525)
      pfam15024
      Location:172 → 726
      Glyco_transf_18; Glycosyltransferase family 18

    18. XM_047444394.1 → XP_047300350.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    19. XM_047444398.1 → XP_047300354.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    20. XM_047444405.1 → XP_047300361.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    21. XM_011511202.3 → XP_011509504.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      See identical proteins and their annotated locations for XP_011509504.1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328
      Conserved Domains (2) summary
      pfam15027
      Location:7 → 138
      DUF4525; Domain of unknown function (DUF4525)
      pfam15024
      Location:172 → 726
      Glyco_transf_18; Glycosyltransferase family 18

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      134559395..134894193
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054342117.1 → XP_054198092.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    2. XM_054342113.1 → XP_054198088.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    3. XM_054342116.1 → XP_054198091.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    4. XM_054342110.1 → XP_054198085.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    5. XM_054342118.1 → XP_054198093.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    6. XM_054342115.1 → XP_054198090.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    7. XM_054342108.1 → XP_054198083.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    8. XM_054342111.1 → XP_054198086.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    9. XM_054342112.1 → XP_054198087.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    10. XM_054342123.1 → XP_054198098.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X2

    11. XM_054342124.1 → XP_054198099.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X2

    12. XM_054342121.1 → XP_054198096.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    13. XM_054342120.1 → XP_054198095.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    14. XM_054342119.1 → XP_054198094.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    15. XM_054342109.1 → XP_054198084.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    16. XM_054342114.1 → XP_054198089.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328

    17. XM_054342122.1 → XP_054198097.1  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A isoform X1

      UniProtKB/Swiss-Prot
      D3DP70, Q09328
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q09328.1 GenPept UniProtKB/Swiss-Prot:Q09328

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