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    Sertm1 serine rich and transmembrane domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 329641, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Sertm1provided by MGI
    Official Full Name
    serine rich and transmembrane domain containing 1provided by MGI
    Primary source
    MGI:MGI:3607715
    See related
    Ensembl:ENSMUSG00000056306 AllianceGenome:MGI:3607715
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    6030405A18Rik
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle. Orthologous to human SERTM1 (serine rich and transmembrane domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in CNS E18 (RPKM 4.5), cortex adult (RPKM 3.7) and 11 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Sertm1 in Genome Data Viewer
    Location:
    3 C; 3 25.9 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (54804489..54823308, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (54897068..54915887, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene splicing factor, arginine/serine-rich 10 pseudogene Neighboring gene regulatory factor X-associated protein Neighboring gene STARR-seq mESC enhancer starr_07687 Neighboring gene predicted gene, 31358 Neighboring gene STARR-seq mESC enhancer starr_07690 Neighboring gene RIKEN cDNA 4931419H13 gene Neighboring gene STARR-seq mESC enhancer starr_07692 Neighboring gene cyclin A1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala. Boyle MP, et al. J Comp Neurol, 2011 Aug 1. PMID 21491433
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    serine-rich and transmembrane domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177854.4 → NP_808522.1  serine-rich and transmembrane domain-containing protein 1

      See identical proteins and their annotated locations for NP_808522.1

      Status: VALIDATED

      Source sequence(s)
      AC142452
      Consensus CDS
      CCDS17355.1
      UniProtKB/Swiss-Prot
      Q8CD78
      Related
      ENSMUSP00000064870.4, ENSMUST00000070342.4
      Conserved Domains (1) summary
      pfam15872
      Location:12 → 106
      SRTM1; Serine-rich and transmembrane domain-containing protein 1

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      54804489..54823308 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8CD78.1 GenPept UniProtKB/Swiss-Prot:Q8CD78

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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