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    Haus5 HAUS augmin-like complex, subunit 5 [ Mus musculus (house mouse) ]

    Gene ID: 71909, updated on 21-Apr-2024

    Summary

    Official Symbol
    Haus5provided by MGI
    Official Full Name
    HAUS augmin-like complex, subunit 5provided by MGI
    Primary source
    MGI:MGI:1919159
    See related
    Ensembl:ENSMUSG00000078762 AllianceGenome:MGI:1919159
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2310022K01Rik
    Summary
    Predicted to be involved in centrosome cycle and spindle assembly. Predicted to act upstream of or within cell division. Predicted to be located in mitotic spindle microtubule. Predicted to be part of HAUS complex. Predicted to be active in centrosome. Orthologous to human HAUS5 (HAUS augmin like complex subunit 5). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 14.0), liver E14.5 (RPKM 13.5) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    Location:
    7 B1; 7 18.95 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (30353133..30364419, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (30653708..30664994, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_18529 Neighboring gene ets variant 2 Neighboring gene RNA binding motif protein 42 Neighboring gene STARR-positive B cell enhancer ABC_E545 Neighboring gene STARR-seq mESC enhancer starr_18530 Neighboring gene STARR-positive B cell enhancer ABC_E6533 Neighboring gene PMIS2 transmembrane protein Neighboring gene predicted gene, 53357

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in centrosome cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in centrosome cycle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spindle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in spindle assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of HAUS complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of HAUS complex ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitotic spindle microtubule ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    HAUS augmin-like complex subunit 5

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027999.1NP_082275.1  HAUS augmin-like complex subunit 5

      See identical proteins and their annotated locations for NP_082275.1

      Status: VALIDATED

      Source sequence(s)
      AI448816, BC089002, BY151175
      Consensus CDS
      CCDS52180.1
      UniProtKB/Swiss-Prot
      Q08EB3, Q0VF86, Q5HZI7, Q6ZQ35, Q8CIK2, Q9D786
      Related
      ENSMUSP00000019697.9, ENSMUST00000019697.9
      Conserved Domains (1) summary
      pfam14817
      Location:8615
      HAUS5; HAUS augmin-like complex subunit 5

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      30353133..30364419 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)