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    H2ac20 H2A clustered histone 20 [ Mus musculus (house mouse) ]

    Gene ID: 319176, updated on 11-Apr-2024

    Summary

    Official Symbol
    H2ac20provided by MGI
    Official Full Name
    H2A clustered histone 20provided by MGI
    Primary source
    MGI:MGI:2448316
    See related
    Ensembl:ENSMUSG00000068855 AllianceGenome:MGI:2448316
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    H2a-613b; Hist2h2ac
    Summary
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. [provided by RefSeq, Aug 2015]
    Orthologs
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    Genomic context

    Location:
    3 F2.1; 3 41.67 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (96127728..96128209, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (96220413..96220880, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene bolA family member 1 Neighboring gene STARR-positive B cell enhancer ABC_E3450 Neighboring gene STARR-positive B cell enhancer ABC_E1023 Neighboring gene H2A clustered histone 21 Neighboring gene H2B clustered histone 21 Neighboring gene H3 clustered histone 15

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleosomal DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of chromatin IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in heterochromatin formation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    part_of nucleosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    histone H2A type 2-C
    Names
    histone 2, H2ac
    histone cluster 2, H2ac

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175662.3NP_783593.1  histone H2A type 2-C

      See identical proteins and their annotated locations for NP_783593.1

      Status: VALIDATED

      Source sequence(s)
      AC125099
      Consensus CDS
      CCDS17634.1
      UniProtKB/Swiss-Prot
      Q64523, Q8CGP3
      UniProtKB/TrEMBL
      A0A0N4SV66, Q149V4
      Related
      ENSMUSP00000088288.4, ENSMUST00000090782.4
      Conserved Domains (1) summary
      PTZ00017
      Location:1129
      PTZ00017; histone H2A; Provisional

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      96127728..96128209 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)