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    Serpinb1a serine (or cysteine) peptidase inhibitor, clade B, member 1a [ Mus musculus (house mouse) ]

    Gene ID: 66222, updated on 9-May-2021

    Summary

    Official Symbol
    Serpinb1aprovided by MGI
    Official Full Name
    serine (or cysteine) peptidase inhibitor, clade B, member 1aprovided by MGI
    Primary source
    MGI:MGI:1913472
    See related
    Ensembl:ENSMUSG00000044734
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    E; L; EI; MN; EIA; ELA; LEI; M/N; PI2; ova; MNEI; M/NEI; ELANH2; AI325983; 1190005M04Rik
    Expression
    Biased expression in large intestine adult (RPKM 90.3), duodenum adult (RPKM 21.7) and 10 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Serpinb1a in Genome Data Viewer
    Location:
    13 A3.2; 13 13.75 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (33026075..33037189, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (32842092..32853206, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (32933961..32943054, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene myosin light chain kinase family, member 4 Neighboring gene Werner helicase interacting protein 1 Neighboring gene serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Neighboring gene predicted gene, 35899

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC129309

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables peptidase inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    contributes_to serine-type endopeptidase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in collagen-containing extracellular matrix HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic ribonucleoprotein granule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in extracellular region ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    leukocyte elastase inhibitor A
    Names
    ovalbumin
    serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1a
    serine (or cysteine) proteinase inhibitor, clade B, member 1a
    serine protease inhibitor EIA
    serpin B1a

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025429.2NP_079705.2  leukocyte elastase inhibitor A

      See identical proteins and their annotated locations for NP_079705.2

      Status: VALIDATED

      Source sequence(s)
      AI325983, AK160167, BY266933
      Consensus CDS
      CCDS26428.1
      UniProtKB/Swiss-Prot
      Q9D154
      Related
      ENSMUSP00000075690.7, ENSMUST00000076352.8
      Conserved Domains (1) summary
      cd19560
      Location:1379
      serpinB1_LEI; serpin family B member 1 (serpin B1), leukocyte elastase inhibitor (LEI)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      33026075..33037189 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030247348.2XP_030103208.1  leukocyte elastase inhibitor A isoform X1

      Conserved Domains (1) summary
      cd19560
      Location:1379
      serpinB1_LEI; serpin family B member 1 (serpin B1), leukocyte elastase inhibitor (LEI)
    2. XM_006516724.3XP_006516787.1  leukocyte elastase inhibitor A isoform X1

      See identical proteins and their annotated locations for XP_006516787.1

      UniProtKB/Swiss-Prot
      Q9D154
      Conserved Domains (1) summary
      cd19560
      Location:1379
      serpinB1_LEI; serpin family B member 1 (serpin B1), leukocyte elastase inhibitor (LEI)
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