Pcdhb14 protocadherin beta 14 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Pcdhb14provided by MGI
Official Full Name: protocadherin beta 14provided by MGI
Primary source: MGI:MGI:2136749
See related: Ensembl:ENSMUSG00000044043 AllianceGenome:MGI:2136749
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: PcdhbN; 2210006M07Rik
Summary: Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in brain. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:: 18 B3; 18 19.5 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	18	NC_000084.7 (37580710..37584147)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	18	NC_000084.6 (37447657..37451094)

Chromosome 18 - NC_000084.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cell adhesion	IBA Inferred from Biological aspect of Ancestor more info
involved_in homophilic cell adhesion via plasma membrane adhesion molecules	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: protocadherin beta-14

Names: PCDH-beta-14; Protocadherin-betaN; cell-cell adhesion molecule

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_053139.3 → NP_444369.3 protocadherin beta-14 precursor

See identical proteins and their annotated locations for NP_444369.3

Status: VALIDATED

Source sequence(s)

AK083065, AY013775, BB622429

Consensus CDS

CCDS29180.1

UniProtKB/Swiss-Prot

Q6PB90, Q8CCT0, Q91Y05

UniProtKB/TrEMBL

Q8K1H2

Related

ENSMUSP00000054111.4, ENSMUST00000052387.5

Conserved Domains (4) summary

cd11304
Location:247 → 343

Cadherin_repeat; Cadherin tandem repeat domain

smart00112
Location:371 → 449

CA; Cadherin repeats

pfam08266
Location:30 → 111

Cadherin_2; Cadherin-like

pfam16492
Location:686 → 768

Cadherin_C_2; Cadherin cytoplasmic C-terminal