U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Tmem87a transmembrane protein 87A [ Mus musculus (house mouse) ]

    Gene ID: 211499, updated on 2-Apr-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Tmem87aprovided by MGI
    Official Full Name
    transmembrane protein 87Aprovided by MGI
    Primary source
    MGI:MGI:2441844
    See related
    Ensembl:ENSMUSG00000033808 AllianceGenome:MGI:2441844
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A930025J12Rik
    Summary
    Predicted to be involved in retrograde transport, endosome to Golgi. Predicted to be integral component of membrane. Predicted to be active in Golgi cisterna membrane. Is expressed in facial ganglion. Orthologous to human TMEM87A (transmembrane protein 87A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in placenta adult (RPKM 9.4), bladder adult (RPKM 9.4) and 28 other tissues See more
    Orthologs
    human all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    2 E5; 2 60.31 cM
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (120185790..120234597, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (120355309..120404154, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene phospholipase A2, group IVF Neighboring gene VPS39 HOPS complex subunit Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:120178706-120178815 Neighboring gene STARR-positive B cell enhancer ABC_E10133 Neighboring gene STARR-positive B cell enhancer ABC_E9071 Neighboring gene glucosidase, alpha; neutral C Neighboring gene RIKEN cDNA 4931402G19 gene Neighboring gene STARR-seq mESC enhancer starr_05508 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:120308865-120309066 Neighboring gene calpain 3 Neighboring gene STARR-seq mESC enhancer starr_05509 Neighboring gene zinc finger protein 106 Neighboring gene STARR-seq mESC enhancer starr_05510

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. BDNF and NT4 play interchangeable roles in gustatory development. Huang T, et al. Dev Biol, 2014 Feb 15. PMID 24378336, Free PMC Article
    2. Epilepsy- and intellectual disability-associated CYFIP2 interacts with both actin regulators and RNA-binding proteins in the neonatal mouse forebrain. Lee Y, et al. Biochem Biophys Res Commun, 2020 Aug 13. PMID 32560809
    3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    4. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
    5. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Touch sensation requires the mechanically gated ion channel ELKIN1.
      Title: Touch sensation requires the mechanically gated ion channel ELKIN1.
    Submit: New GeneRIF Correction

    Variation

    Go to the top of the page Help

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to mechanical stimulus ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in retrograde transport, endosome to Golgi IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in retrograde transport, endosome to Golgi ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in Golgi cisterna membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi cisterna membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in ruffle ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    transmembrane protein 87A
    Names
    elkin1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110496.1 → NP_001103966.1  transmembrane protein 87A isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AK044591, AL844608, BY149198
      Consensus CDS
      CCDS50677.1
      UniProtKB/Swiss-Prot
      Q8BTV9, Q8BU98, Q8BXN9, Q8R2P9, Q8R3S7
      UniProtKB/TrEMBL
      A2AQJ5
      Related
      ENSMUSP00000087496.6, ENSMUST00000090042.12
      Conserved Domains (1) summary
      pfam06814
      Location:210 → 471
      Lung_7-TM_R; Lung seven transmembrane receptor

    2. NM_001110497.1 → NP_001103967.1  transmembrane protein 87A isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      AK086738, AL844608, BY149198
      UniProtKB/Swiss-Prot
      Q8BTV9, Q8BU98, Q8BXN9, Q8R2P9, Q8R3S7
      Conserved Domains (1) summary
      pfam06814
      Location:210 → 471
      Lung_7-TM_R; Lung seven transmembrane receptor

    3. NM_173734.3 → NP_776095.2  transmembrane protein 87A isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      AK044591, AK134268, AL844608, BY149198
      Consensus CDS
      CCDS50678.1
      UniProtKB/Swiss-Prot
      Q8BTV9, Q8BU98, Q8BXN9, Q8R2P9, Q8R3S7
      UniProtKB/TrEMBL
      A2AQJ6
      Related
      ENSMUSP00000087500.6, ENSMUST00000090046.12
      Conserved Domains (1) summary
      pfam06814
      Location:210 → 472
      Lung_7-TM_R; Lung seven transmembrane receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      120185790..120234597 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006499077.3 → XP_006499140.1  transmembrane protein 87A isoform X1

      UniProtKB/Swiss-Prot
      Q8BTV9, Q8BU98, Q8BXN9, Q8R2P9, Q8R3S7
      Related
      ENSMUST00000136410.8
      Conserved Domains (1) summary
      pfam06814
      Location:186 → 472
      Lung_7-TM_R; Lung seven transmembrane receptor

    2. XM_011239411.2 → XP_011237713.1  transmembrane protein 87A isoform X4

      Conserved Domains (1) summary
      pfam06814
      Location:43 → 329
      Lung_7-TM_R; Lung seven transmembrane receptor

    3. XM_011239409.1 → XP_011237711.1  transmembrane protein 87A isoform X2

      UniProtKB/Swiss-Prot
      Q8BTV9, Q8BU98, Q8BXN9, Q8R2P9, Q8R3S7
      Conserved Domains (1) summary
      pfam06814
      Location:138 → 424
      Lung_7-TM_R; Lung seven transmembrane receptor

    4. XM_011239410.3 → XP_011237712.1  transmembrane protein 87A isoform X3

      UniProtKB/TrEMBL
      A2AQJ7
      Related
      ENSMUSP00000106357.2, ENSMUST00000110729.2
      Conserved Domains (1) summary
      pfam06814
      Location:186 → 472
      Lung_7-TM_R; Lung seven transmembrane receptor

    5. XM_011239412.4 → XP_011237714.1  transmembrane protein 87A isoform X5

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BXN9.1 GenPept UniProtKB/Swiss-Prot:Q8BXN9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous