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    Pde1c phosphodiesterase 1C [ Mus musculus (house mouse) ]

    Gene ID: 18575, updated on 3-Apr-2024

    Summary

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    Official Symbol
    Pde1cprovided by MGI
    Official Full Name
    phosphodiesterase 1Cprovided by MGI
    Primary source
    MGI:MGI:108413
    See related
    Ensembl:ENSMUSG00000004347 AllianceGenome:MGI:108413
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable cAMP binding activity; calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity; and calmodulin-dependent cyclic-nucleotide phosphodiesterase activity. Acts upstream of or within sensory perception of smell. Located in cilium. Is expressed in several structures, including alimentary system; integumental system; male reproductive gland or organ; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 74. Orthologous to human PDE1C (phosphodiesterase 1C). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis adult (RPKM 4.7), cerebellum adult (RPKM 3.2) and 8 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Pde1c in Genome Data Viewer
    Location:
    6 B3; 6 27.65 cM
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (56046783..56629590, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (56069798..56652510, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_15984 Neighboring gene protein phosphatase 1, regulatory subunit 17 Neighboring gene STARR-seq mESC enhancer starr_15985 Neighboring gene ribosomal protein L17 pseudogene Neighboring gene STARR-seq mESC enhancer starr_15986 Neighboring gene STARR-positive B cell enhancer mm9_chr6:56183581-56183882 Neighboring gene STARR-seq mESC enhancer starr_15987 Neighboring gene STARR-seq mESC enhancer starr_15988 Neighboring gene predicted gene, 34753 Neighboring gene STARR-seq mESC enhancer starr_15989 Neighboring gene predicted gene, 24709 Neighboring gene predicted gene, 22493 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:56654682-56654884 Neighboring gene STARR-seq mESC enhancer starr_15990 Neighboring gene STARR-positive B cell enhancer ABC_E679 Neighboring gene LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated Neighboring gene AVL9 cell migration associated

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Multiprotein Complex With TRPC (Transient Receptor Potential-Canonical) Channel, PDE1C (Phosphodiesterase 1C), and A2R (Adenosine A2 Receptor) Plays a Critical Role in Regulating Cardiomyocyte cAMP and Survival. Zhang Y, et al. Circulation, 2018 Oct 30. PMID 29871977, Free PMC Article
    2. PDE1C deficiency antagonizes pathological cardiac remodeling and dysfunction. Knight WE, et al. Proc Natl Acad Sci U S A, 2016 Nov 8. PMID 27791092, Free PMC Article
    3. Calcium-dependent phosphodiesterase 1C inhibits renin release from isolated juxtaglomerular cells. Ortiz-Capisano MC, et al. Am J Physiol Regul Integr Comp Physiol, 2009 Nov. PMID 19741056, Free PMC Article
    4. The calmodulin-dependent phosphodiesterase gene PDE1C encodes several functionally different splice variants in a tissue-specific manner. Yan C, et al. J Biol Chem, 1996 Oct 11. PMID 8810348
    5. Cyclic nucleotide phosphodiesterase 1C contributes to abdominal aortic aneurysm. Zhang C, et al. Proc Natl Acad Sci U S A, 2021 Aug 3. PMID 34312235, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Cyclic nucleotide phosphodiesterase 1C contributes to abdominal aortic aneurysm.
      Title: Cyclic nucleotide phosphodiesterase 1C contributes to abdominal aortic aneurysm.
    2. By whole-mount immunofluorescence on postnatal day 3 mouse cochlea, we show its expression in outer (OHC) and inner (IHC) hair cells cytosol co-localizing with Lamp-1 in lysosomes. Furthermore, we provide evidence that the variant alters the PDE1C hydrolytic activity for both cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP).
      Title: A dominant variant in the PDE1C gene is associated with nonsyndromic hearing loss.
    3. Cardiac Pde1C is a direct transcriptional target of PPARalpha.
      Title: Mouse Cardiac Pde1C Is a Direct Transcriptional Target of Pparα.
    4. Ligation injury caused a marked increase in neointimal and medial thickening in PDE1C+/+ mice. Injury-induced neointimal formation was significantly attenuated by PDE1C deficiency (knockout mice) or PDE1 inhibition in vivo.
      Title: Role of cAMP-phosphodiesterase 1C signaling in regulating growth factor receptor stability, vascular smooth muscle cell growth, migration, and neointimal hyperplasia.
    5. PDE1C is expressed in isolated juxtaglomerular cells, and contributes to calcium's inhibitory modulation of renin release from juxtaglomerular cells.
      Title: Calcium-dependent phosphodiesterase 1C inhibits renin release from isolated juxtaglomerular cells.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2)  1 citation
    • Endonuclease-mediated (3) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 3',5'-cyclic-AMP phosphodiesterase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 3',5'-cyclic-AMP phosphodiesterase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables 3',5'-cyclic-GMP phosphodiesterase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 3',5'-cyclic-GMP phosphodiesterase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables 3',5'-cyclic-nucleotide phosphodiesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cAMP binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    enables calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphoric diester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cAMP-mediated signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of insulin secretion involved in cellular response to glucose stimulus ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within response to calcium ion ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    acts_upstream_of_or_within sensory perception of smell IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within sensory perception of smell IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cilium IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in lysosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in neuronal cell body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
    Names
    3',5'-cyclic-AMP phosphodiesterase
    3',5'-cyclic-GMP phosphodiesterase
    calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
    cam-PDE 1C
    dual specificity Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
    NP_001020739.1
    NP_001153424.1
    NP_001153425.1
    NP_001153427.1
    NP_001153428.1
    NP_001153429.1
    NP_001153432.1
    NP_001342404.1
    NP_001397182.1
    NP_001397183.1
    NP_001397184.1
    NP_001397185.1
    NP_001397186.1
    NP_001397187.1
    NP_035184.1
    XP_006505793.1
    XP_006505797.1
    XP_006505798.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025568.3 → NP_001020739.1  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform b

      See identical proteins and their annotated locations for NP_001020739.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) represents the longest transcript. Variants 2 and 8 encode the same isoform (b).
      Source sequence(s)
      AC079274, AC079956
      Consensus CDS
      CCDS51785.1
      UniProtKB/TrEMBL
      Q3USZ6, Q5D0E7
      Related
      ENSMUSP00000131350.2, ENSMUST00000166102.8
      Conserved Domains (3) summary
      PTZ00121
      Location:543 → 628
      PTZ00121; MAEBL; Provisional
      pfam00233
      Location:227 → 455
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
      pfam08499
      Location:86 → 142
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal

    2. NM_001159952.2 → NP_001153424.1  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an in-frame exon in the 5' coding region, compared to variant 2. This results in a shorter protein (isoform c), compared to isoform b.
      Source sequence(s)
      AC079274, AC079956
      Consensus CDS
      CCDS51783.1
      UniProtKB/TrEMBL
      E9Q7V6, Q3USZ6
      Related
      ENSMUSP00000130139.2, ENSMUST00000164037.3
      Conserved Domains (2) summary
      pfam00233
      Location:218 → 446
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
      pfam08499
      Location:77 → 133
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal

    3. NM_001159953.2 → NP_001153425.1  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform d

      See identical proteins and their annotated locations for NP_001153425.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) uses an alternate exon structure in the 3' coding region compared to variant 2. It encodes isoform d, which is longer and has a distinct C-terminus, compared to isoform b.
      Source sequence(s)
      AC079274, AC079365, AC079956
      Consensus CDS
      CCDS51784.1
      UniProtKB/Swiss-Prot
      Q62045, Q64338, Q8BSV6
      UniProtKB/TrEMBL
      Q3USZ6
      Related
      ENSMUSP00000046601.8, ENSMUST00000044505.14
      Conserved Domains (2) summary
      pfam00233
      Location:227 → 455
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
      pfam08499
      Location:86 → 142
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal

    4. NM_001159955.2 → NP_001153427.1  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform a

      See identical proteins and their annotated locations for NP_001153427.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR and uses an alternate 3' exon structure compared to variant 2. Variants 1, 7 and 9 encode the same isoform (a), which is longer and has a distinct C-terminus, compared to isoform b.
      Source sequence(s)
      AC044804, AC079274, AC079365, AC079956
      Consensus CDS
      CCDS20170.1
      UniProtKB/TrEMBL
      Q3USZ6
      Related
      ENSMUSP00000128364.2, ENSMUST00000168944.8
      Conserved Domains (3) summary
      pfam00233
      Location:227 → 445
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
      pfam08499
      Location:86 → 142
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal
      cl26511
      Location:543 → 633
      Neuromodulin_N; Gap junction protein N-terminal region

    5. NM_001159956.2 → NP_001153428.1  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform f

      See identical proteins and their annotated locations for NP_001153428.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR, 5' coding region, and 3' coding region, compared to variant 2. This results in distinct N- and C-termini and a shorter protein (isoform f), compared to isoform b.
      Source sequence(s)
      AC044804, AC079365, AC079956
      Consensus CDS
      CCDS51786.1
      UniProtKB/TrEMBL
      Q3USZ6, Q9D5W0
      Related
      ENSMUSP00000133170.2, ENSMUST00000170774.8
      Conserved Domains (2) summary
      pfam00233
      Location:190 → 418
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
      pfam08499
      Location:49 → 105
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal

    6. NM_001159957.2 → NP_001153429.1  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform e

      See identical proteins and their annotated locations for NP_001153429.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR and 5' coding region but maintains the reading frame, compared to variant 2. This results in a distinct N-terminus and shorter protein (isoform e), compared to isoform b.
      Source sequence(s)
      AC044804, AC079274, AC079956
      Consensus CDS
      CCDS51787.1
      UniProtKB/TrEMBL
      Q3USZ6, Q8CDV2
      Related
      ENSMUSP00000131892.2, ENSMUST00000166890.8
      Conserved Domains (2) summary
      pfam00233
      Location:199 → 427
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
      pfam08499
      Location:58 → 114
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal

    7. NM_001159960.2 → NP_001153432.1  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform b

      See identical proteins and their annotated locations for NP_001153432.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) differs in the 5' UTR, compared to variant 2. Variants 2 and 8 encode the same isoform (b).
      Source sequence(s)
      AC044804, AC079274, AC079956
      Consensus CDS
      CCDS51785.1
      UniProtKB/TrEMBL
      Q3USZ6, Q5D0E7
      Related
      ENSMUSP00000129185.2, ENSMUST00000164752.8
      Conserved Domains (3) summary
      PTZ00121
      Location:543 → 628
      PTZ00121; MAEBL; Provisional
      pfam00233
      Location:227 → 455
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
      pfam08499
      Location:86 → 142
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal

    8. NM_001355475.2 → NP_001342404.1  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9) uses an alternate 3' exon structure compared to variant 2. Variants 1, 7 and 9 encode the same isoform (a), which is longer and has a distinct C-terminus, compared to isoform b.
      Source sequence(s)
      AC079274, AC079365, AC079956
      Consensus CDS
      CCDS20170.1
      UniProtKB/TrEMBL
      Q3USZ6
      Conserved Domains (3) summary
      pfam00233
      Location:227 → 445
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
      pfam08499
      Location:86 → 142
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal
      cl26511
      Location:543 → 633
      Neuromodulin_N; Gap junction protein N-terminal region

    9. NM_001410253.1 → NP_001397182.1  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform b

      Status: VALIDATED

      Source sequence(s)
      AC079274, AC079956
      UniProtKB/TrEMBL
      Q5D0E7

    10. NM_001410254.1 → NP_001397183.1  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform b

      Status: VALIDATED

      Source sequence(s)
      AC044804, AC079274, AC079956
      UniProtKB/TrEMBL
      Q5D0E7

    11. NM_001410255.1 → NP_001397184.1  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform g

      Status: VALIDATED

      Source sequence(s)
      AC044804, AC079956, AC122847

    12. NM_001410256.1 → NP_001397185.1  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform h

      Status: VALIDATED

      Source sequence(s)
      AC044804, AC079365, AC079956

    13. NM_001410257.1 → NP_001397186.1  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform i

      Status: VALIDATED

      Source sequence(s)
      AC044804, AC079365, AC079956

    14. NM_001410258.1 → NP_001397187.1  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform j

      Status: VALIDATED

      Source sequence(s)
      AC044804, AC079956

    15. NM_011054.5 → NP_035184.1  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform a

      See identical proteins and their annotated locations for NP_035184.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) differs in the 5' UTR and uses an alternate 3' exon structure compared to variant 2. Variants 1, 7 and 9 encode the same isoform (a), which is longer and has a distinct C-terminus, compared to isoform b.
      Source sequence(s)
      AC079274, AC079365, AC079956
      Consensus CDS
      CCDS20170.1
      UniProtKB/TrEMBL
      Q3USZ6
      Related
      ENSMUSP00000109966.3, ENSMUST00000114327.9
      Conserved Domains (3) summary
      pfam00233
      Location:227 → 445
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
      pfam08499
      Location:86 → 142
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal
      cl26511
      Location:543 → 633
      Neuromodulin_N; Gap junction protein N-terminal region

    RNA

    1. NR_176965.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC044804, AC079274, AC079365, AC079956

    2. NR_176966.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC044804, AC079365, AC079956

    3. NR_176967.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC044804, AC079365, AC079956

    4. NR_176968.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC079274, AC079365, AC079956

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      56046783..56629590 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006505730.5 → XP_006505793.1  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform X1

      UniProtKB/TrEMBL
      A0A5F8MPG4
      Related
      ENSMUSP00000158960.2, ENSMUST00000239143.2
      Conserved Domains (3) summary
      PTZ00121
      Location:698 → 788
      PTZ00121; MAEBL; Provisional
      pfam00233
      Location:382 → 610
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
      pfam08499
      Location:241 → 297
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal

    2. XM_006505734.2 → XP_006505797.1  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform X3

      UniProtKB/TrEMBL
      A0A0N4SWG4
      Related
      ENSMUSP00000145508.2, ENSMUST00000203372.3
      Conserved Domains (3) summary
      PTZ00121
      Location:603 → 693
      PTZ00121; MAEBL; Provisional
      pfam00233
      Location:287 → 515
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
      pfam08499
      Location:146 → 202
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal

    3. XM_006505735.3 → XP_006505798.3  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform X4

      UniProtKB/TrEMBL
      Q3USZ6
      Conserved Domains (3) summary
      PTZ00121
      Location:537 → 627
      PTZ00121; MAEBL; Provisional
      pfam00233
      Location:221 → 449
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
      pfam08499
      Location:80 → 136
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal

    RNA

    1. XR_003956167.1 RNA Sequence

    2. XR_003956169.1 RNA Sequence

    3. XR_003956168.1 RNA Sequence

    4. XR_003956172.1 RNA Sequence

    5. XR_003956171.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q64338.2 GenPept UniProtKB/Swiss-Prot:Q64338

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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