Krt83 keratin 83 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Krt83provided by MGI
Official Full Name: keratin 83provided by MGI
Primary source: MGI:MGI:3690448
See related: Ensembl:ENSMUSG00000067613 AllianceGenome:MGI:3690448
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 5430421N21Rik
Summary: Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis et progressiva 5; hair disease; and monilethrix. Orthologous to human KRT81 (keratin 81) and KRT83 (keratin 83). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in subcutaneous fat pad adult (RPKM 3.0), ovary adult (RPKM 0.7) and 3 other tissues See more
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Genomic context

Location:: 15 F2; 15 56.9 cM

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	15	NC_000081.7 (101383011..101389393, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	15	NC_000081.6 (101485130..101491512, complement)

Chromosome 15 - NC_000081.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

NoName (e-PCR)
- UniSTS:490772

AI325212 (e-PCR)
- UniSTS:180839

NoName (e-PCR)
- UniSTS:224897

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables structural constituent of skin epidermis	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in intermediate filament organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in keratinization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in keratin filament	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: type II hair keratin

Names: keratin type II

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001201323.1 → NP_001188252.1 type II hair keratin

Status: VALIDATED

Source sequence(s)

AI561926, AK133718

Consensus CDS

CCDS49735.1

UniProtKB/TrEMBL

E9Q1Y9, Q61726

Related

ENSMUSP00000023718.8, ENSMUST00000023718.9

Conserved Domains (3) summary

pfam00038
Location:103 → 414

Filament; Intermediate filament protein

pfam16208
Location:38 → 100

Keratin_2_head; Keratin type II head

cl23720
Location:313 → 381

RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)