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    Spmip9 sperm microtubule inner protein 9 [ Mus musculus (house mouse) ]

    Gene ID: 74221, updated on 21-Apr-2024

    Summary

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    Official Symbol
    Spmip9provided by MGI
    Official Full Name
    sperm microtubule inner protein 9provided by MGI
    Primary source
    MGI:MGI:1921471
    See related
    Ensembl:ENSMUSG00000051896 AllianceGenome:MGI:1921471
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tex37; Tsc21; 1700011F03Rik
    Summary
    Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human TEX37 (testis expressed 37). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 105.0) See more
    Orthologs
    human all
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    Genomic context

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    Location:
    6 C1; 6 32.12 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (70890073..70928078, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (70913089..70951095, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_16241 Neighboring gene STARR-positive B cell enhancer mm9_chr6:70761912-70762213 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:70764223-70764410 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:70765584-70765767 Neighboring gene predicted gene, 30331 Neighboring gene STARR-seq mESC enhancer starr_16242 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:70779525-70779708 Neighboring gene eukaryotic translation initiation factor 2 alpha kinase 3 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:70812737-70812920 Neighboring gene predicted gene, 23346 Neighboring gene STARR-positive B cell enhancer ABC_E6438 Neighboring gene STARR-positive B cell enhancer ABC_E4832 Neighboring gene STARR-seq mESC enhancer starr_16244 Neighboring gene forkhead box I3 Neighboring gene predicted gene, 57755

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification and characteristics of a novel testis-specific gene, Tsc21, in mice and human. Yu Z, et al. Mol Biol Rep, 2007 Jun. PMID 17091336
    2. The evolutionarily conserved genes: Tex37, Ccdc73, Prss55 and Nxt2 are dispensable for fertility in mice. Khan M, et al. Sci Rep, 2018 Mar 21. PMID 29563520, Free PMC Article
    3. Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression. West DB, et al. PLoS Genet, 2016 Feb. PMID 26839965, Free PMC Article
    4. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    5. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 
    • Endonuclease-mediated (2)  1 citation

    General gene information

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    Homology

    Clone Names

    • MGC58753

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in axonemal A tubule inner sheath IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein SPMIP9
    Names
    protein TSC21
    testis expressed 37
    testis-expressed sequence 37 protein
    testis-specific conserved protein of 21 kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355766.1 → NP_001342695.1  protein SPMIP9 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK005862
      Conserved Domains (1) summary
      pfam15217
      Location:1 → 179
      TSC21; TSC21 family

    2. NM_028825.3 → NP_083101.1  protein SPMIP9 isoform 1

      See identical proteins and their annotated locations for NP_083101.1

      Status: VALIDATED

      Source sequence(s)
      AK005862
      Consensus CDS
      CCDS20224.1
      UniProtKB/Swiss-Prot
      Q810N1, Q9DAG4
      Related
      ENSMUSP00000066786.5, ENSMUST00000063456.5
      Conserved Domains (1) summary
      pfam15217
      Location:1 → 180
      TSC21; TSC21 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      70890073..70928078 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030255637.2 → XP_030111497.1  protein SPMIP9 isoform X2

      Conserved Domains (1) summary
      pfam15217
      Location:34 → 213
      TSC21; TSC21 family

    2. XM_030255636.1 → XP_030111496.1  protein SPMIP9 isoform X1

      Conserved Domains (1) summary
      pfam15217
      Location:1 → 179
      TSC21; TSC21 family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9DAG4.1 GenPept UniProtKB/Swiss-Prot:Q9DAG4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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