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    Zfp963 zinc finger protein 963 [ Mus musculus (house mouse) ]

    Gene ID: 620419, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Zfp963provided by MGI
    Official Full Name
    zinc finger protein 963provided by MGI
    Primary source
    MGI:MGI:4867078
    See related
    Ensembl:ENSMUSG00000092260 AllianceGenome:MGI:4867078
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including ZNF44 (zinc finger protein 44); ZNF442 (zinc finger protein 442); and ZNF563 (zinc finger protein 563). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E14 (RPKM 3.7), CNS E11.5 (RPKM 3.5) and 28 other tissues See more
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    Genomic context

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    Location:
    8 B3.3; 8 33.88 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (70194289..70202612, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (69741639..69749962, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 869 Neighboring gene STARR-positive B cell enhancer ABC_E9117 Neighboring gene STARR-positive B cell enhancer ABC_E242 Neighboring gene predicted gene, 51532 Neighboring gene STARR-positive B cell enhancer ABC_E6642 Neighboring gene STARR-seq mESC enhancer starr_21745 Neighboring gene predicted gene, 19893 Neighboring gene zinc finger protein 866 Neighboring gene STARR-positive B cell enhancer ABC_E6643

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Potential readthrough

    Included gene: Zfp866

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 669-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001200023.1 → NP_001186952.1  zinc finger protein 669-like

      Status: VALIDATED

      Source sequence(s)
      AC157564, AK162670
      Consensus CDS
      CCDS52566.1
      UniProtKB/TrEMBL
      D3Z2T8
      Related
      ENSMUSP00000119087.2, ENSMUST00000130458.8
      Conserved Domains (5) summary
      smart00349
      Location:4 → 44
      KRAB; krueppel associated box
      COG5048
      Location:185 → 383
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:298 → 318
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:4 → 41
      KRAB; KRAB box
      pfam13465
      Location:338 → 363
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      70194289..70202612 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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