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    Zfp719 zinc finger protein 719 [ Mus musculus (house mouse) ]

    Gene ID: 210105, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Zfp719provided by MGI
    Official Full Name
    zinc finger protein 719provided by MGI
    Primary source
    MGI:MGI:2444708
    See related
    Ensembl:ENSMUSG00000030469 AllianceGenome:MGI:2444708
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mszf6; 8030458J18; 9430094P17Rik; C630016O21Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Is expressed in bladder; male associated reproductive structure; testis; ureter; and urethra of male. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 2.3), cerebellum adult (RPKM 2.2) and 26 other tissues See more
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    Genomic context

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    See Zfp719 in Genome Data Viewer
    Location:
    7 B3; 7 28.25 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (43228988..43243134)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (43579559..43593710)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene CD33 molecule Neighboring gene zinc finger protein 658 Neighboring gene STARR-positive B cell enhancer ABC_E9290 Neighboring gene STARR-seq mESC enhancer starr_18778 Neighboring gene STARR-seq mESC enhancer starr_18779 Neighboring gene zinc finger protein 819 Neighboring gene CEA cell adhesion molecule 18

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A gene expression resource generated by genome-wide lacZ profiling in the mouse. Tuck E, et al. Dis Model Mech, 2015 Nov. PMID 26398943, Free PMC Article
    2. Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR. Agata Y, et al. Gene, 1998 Jun 15. PMID 9630514
    3. A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. Wiese CB, et al. Front Neurosci, 2012. PMID 22988430, Free PMC Article
    4. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
    5. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 719

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357769.1 → NP_001344698.1  zinc finger protein 719

      Status: VALIDATED

      Source sequence(s)
      AC154108
      Consensus CDS
      CCDS52225.1
      UniProtKB/TrEMBL
      Q8BIV1
      Conserved Domains (3) summary
      COG5048
      Location:335 → 708
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:567 → 587
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:48 → 89
      KRAB; KRAB box

    2. NM_172482.1 → NP_766070.1  zinc finger protein 719

      See identical proteins and their annotated locations for NP_766070.1

      Status: VALIDATED

      Source sequence(s)
      AC154108, AK044684, AK083143, BB684430, CJ086175
      Consensus CDS
      CCDS52225.1
      UniProtKB/TrEMBL
      Q8BIV1
      Related
      ENSMUSP00000050968.8, ENSMUST00000058104.8
      Conserved Domains (3) summary
      COG5048
      Location:335 → 708
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:567 → 587
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:48 → 89
      KRAB; KRAB box

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      43228988..43243134
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036152866.1 → XP_036008759.1  zinc finger protein 719 isoform X2

      Conserved Domains (3) summary
      COG5048
      Location:295 → 668
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:527 → 547
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:8 → 49
      KRAB; KRAB box

    2. XM_011250841.4 → XP_011249143.1  zinc finger protein 719 isoform X3

      See identical proteins and their annotated locations for XP_011249143.1

      Conserved Domains (2) summary
      COG5048
      Location:258 → 631
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:490 → 510
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_036152865.1 → XP_036008758.1  zinc finger protein 719 isoform X1

      UniProtKB/TrEMBL
      Q8BIV1
      Conserved Domains (3) summary
      COG5048
      Location:335 → 708
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:567 → 587
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:48 → 89
      KRAB; KRAB box
    Nucleotide Protein Strain
    Heading Accession and Version

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