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    Minar2 membrane integral NOTCH2 associated receptor 2 [ Mus musculus (house mouse) ]

    Gene ID: 225583, updated on 23-Jun-2021

    Summary

    Official Symbol
    Minar2provided by MGI
    Official Full Name
    membrane integral NOTCH2 associated receptor 2provided by MGI
    Primary source
    MGI:MGI:2442934
    See related
    Ensembl:ENSMUSG00000050875
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A730017C20Rik
    Expression
    Biased expression in CNS E18 (RPKM 36.1), whole brain E14.5 (RPKM 32.1) and 6 other tissues See more
    Orthologs
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    Try the new Transcript table

    Genomic context

    See Minar2 in Genome Data Viewer
    Location:
    18; 18 D3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (59195264..59210034)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (59062189..59076962)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (59222035..59236616)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA48 Neighboring gene a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene predicted gene, 54033 Neighboring gene chondroitin sulfate synthase 3 Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    major intrinsically disordered NOTCH2-binding receptor 1-like homolog
    Names
    UPF0258 protein KIAA1024-like homolog
    major intrinsically disordered Notch2-binding receptor 1-like homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001167925.2NP_001161397.2  major intrinsically disordered NOTCH2-binding receptor 1-like homolog isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) encodes the longer isoform (c).
      Source sequence(s)
      AC132242, CO044279
      Conserved Domains (1) summary
      pfam06789
      Location:101208
      UPF0258; uncharacterized protein family (UPF0258)
    2. NM_173759.5NP_776120.3  major intrinsically disordered NOTCH2-binding receptor 1-like homolog isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region, compared to variant 2, resulting in an isoform (a) that is shorter than isoform c.
      Source sequence(s)
      AC132242, BY125990, CO044279
      Consensus CDS
      CCDS29267.2
      UniProtKB/TrEMBL
      E9Q5J6
      Related
      ENSMUSP00000125952.3, ENSMUST00000165666.9
      Conserved Domains (1) summary
      pfam06789
      Location:52191
      UPF0258; uncharacterized protein family (UPF0258)

    RNA

    1. NR_033764.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) includes an additional internal exon, compared to variant 2. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 2, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC132242, AK080452, CO044279
    2. NR_033765.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) includes an additional internal exon, compared to variant 2. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 2, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC132242, BC075669
      Related
      ENSMUST00000117064.8

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      59195264..59210034
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036161119.1XP_036017012.1  major intrinsically disordered NOTCH2-binding receptor 1-like homolog isoform X1

      Conserved Domains (1) summary
      pfam06789
      Location:25177
      UPF0258; Uncharacterized protein family (UPF0258)
    2. XM_006525878.5XP_006525941.1  major intrinsically disordered NOTCH2-binding receptor 1-like homolog isoform X2

      See identical proteins and their annotated locations for XP_006525941.1

      UniProtKB/Swiss-Prot
      Q8C4X7
      UniProtKB/TrEMBL
      A0A0R4J0Q0
      Related
      ENSMUSP00000113023.2, ENSMUST00000118510.8
      Conserved Domains (1) summary
      pfam06789
      Location:42149
      UPF0258; Uncharacterized protein family (UPF0258)
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